SURVIVAL OF OPERATED BRONCHUS CARCINOMA PATIENTS - A PROSPECTIVE-STUDY
SURVIVAL OF OPERATED BRONCHUS CARCINOMA PATIENTS - A PROSPECTIVE-STUDY
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DOI：
10.1002/jso.2930360203
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发表时间：
1987-10-01
影响因子：
2.5
通讯作者：
VOGTMOYKOPF, I
中科院分区：
文献类型：
--
作者：
KAYSER, KW;BULZEBRUCK, H;VOGTMOYKOPF, I
测量了 282 例原发性支气管癌手术标本的最大直径、肿瘤体积和宿主组织的炎症反应。分析细胞类型、pT 和 pN 阶段、原代细胞的最大直径和体积以及宿主组织的炎症反应与患者生存的关系。通过每季度与家庭医生的沟通来评估死亡日期。通过使用 Kaplan-Meier 估计计算存活率。所有患者的平均生存期按 480 天计算。研究发现淋巴结受累和肿瘤体积对生存有重大影响。根据肿瘤最大直径对生存的微弱贡献，pT1 和 pT2 阶段之间的生存没有发现重大差异。如果在肿瘤边界注意到严重的炎症反应，则患者在所有肿瘤阶段的生存率都会略有增加。发现细胞类型和肿瘤分级对生存的影响较小。
Maximum diameter, tumour volume, and inflammatory response of host tissue in 282 surgical specimens with primary carcinoma of the bronchus were measured. Cell type, pT- and pN-stage, maximum diameter and volume of the primaries, and inflammatory response of host tissue were analyzed in respect to survival of the patients. Date of death was evaluated by quarterly communications with the house physicians. Survival rates were computed by use of Kaplan-Meier estimation. Mean survival of all patients was calculated at 480 days. Lymph node involvement and tumour volume were found to have a major influence on survival. In accordance with the weak contribution of maximum diameter of the tumour to survival, no major differences in survival between pT1- and pT2-stage were found. If severe inflammatory response at the tumour boundary was noted, patients showed slightly increased survival in all tumour stages. Cell type and tumour grading were found to be of minor influence in respect to survival.