How concepts are encoded in the human brain: A modality independent, category-based cortical organization of semantic knowledge
How concepts are encoded in the human brain: A modality independent, category-based cortical organization of semantic knowledge
复制标题
DOI：
10.1016/j.neuroimage.2016.04.063
复制
发表时间：
2016-07-15
期刊：
影响因子：
5.7
通讯作者：
Pietrini, Pietro
中科院分区：
文献类型：
--
作者：
Handjaras, Giacomo;Ricciardi, Emiliano;Pietrini, Pietro
概念性知识是如何在人脑中表现出来的还有待确定。为了解决基于低级感觉和高级抽象特征在语义处理中的差异作用，我们将视觉和/或听觉方式呈现的八个类别的具体名词执行属性生成任务时，视力正常和先天失明个体的语言产生行为研究和脑活动测量相结合。由海马体旁、枕侧、颞顶枕和下顶叶皮质组成的大型语义皮质网络中的神经活动模式与语言产生相关，并且独立于刺激呈现的方式（视觉或听觉）和（缺乏）视觉经验。相比之下，只有当分析仅限于语义皮质网络中的单个区域时，才会观察到选择的模态依赖差异。我们得出的结论是，人类大脑中的概念知识依赖于一个分布式的、与模式无关的皮层表征，该表征整合了保留在区域水平上的部分类别和特定模式的信息。(C) 2016年作者。Elsevier Inc.出版。
How conceptual knowledge is represented in the human brain remains to be determined. To address the differential role of low-level sensory-based and high-level abstract features in semantic processing, we combined behavioral studies of linguistic production and brain activity measures by functional magnetic resonance imaging in sighted and congenitally blind individuals while they performed a property-generation task with concrete nouns from eight categories, presented through visual and/or auditory modalities.Patterns of neural activity within a large semantic cortical network that comprised parahippocampal, lateral occipital, temporo-parieto-occipital and inferior parietal cortices correlated with linguistic production and were independent both from the modality of stimulus presentation (either visual or auditory) and the (lack of) visual experience. In contrast, selected modality-dependent differences were observed only when the analysis was limited to the individual regions within the semantic cortical network.We conclude that conceptual knowledge in the human brain relies on a distributed, modality-independent cortical representation that integrates the partial category and modality specific information retained at a regional level. (C) 2016 The Authors. Published by Elsevier Inc.