ULTRASTRUCTURAL VARIATIONS OF NUCLEAR BODIES IN HUMAN DISEASES
ULTRASTRUCTURAL VARIATIONS OF NUCLEAR BODIES IN HUMAN DISEASES
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DOI：
10.1016/s0022-5320(67)80074-1
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发表时间：
1967-01-01
期刊：
影响因子：
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通讯作者：
DELARUE, J
中科院分区：
文献类型：
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作者：
BOUTEILLE, M;KALIFAT, SR;DELARUE, J
在15种不同类型的人类疾病和1种实验性肿瘤的67例病例中经常观察到核体，并与文献中描述的核体进行比较。根据其超微结构发育程度，提出了5种不同类型的分类。这种包涵体通常在肿瘤、病毒感染的物质和参与分泌的细胞中观察到。它们也可以在正常组织中找到。核小体与细胞过度活跃有关，其原因可能是生理性的、激素性的、药物诱导的、病毒性的或肿瘤性的。
Nuclear bodies were frequently observed in 67 cases of 15 different types of human disease and 1 experimental tumor and compared to those described in the literature. A classification of 5 different types is proposed, depending on their degree of ultra-structural development. Such inclusions are often observed in tumors, in virus-infected material, and in cells involved in secretion. They may also be found in normal tissues. Nuclear bodies are related to cellular hyperactivity, the cause of which may be physiological, hormonal, drug-induced, viral, or tumoral.