The EUROCARE-3 database: methodology of data collection, standardisation, quality control and statistical analysis
The EUROCARE-3 database: methodology of data collection, standardisation, quality control and statistical analysis
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DOI：
10.1093/annonc/mdg751
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发表时间：
2003-12-01
影响因子：
50.5
通讯作者：
Tavilla, A.
中科院分区：
文献类型：
--
作者：
Capocaccia, R.;Gatta, G.;Tavilla, A.
EUROCARE数据库包含了22个欧洲国家67个癌症登记处涵盖的人口中1978年至1994年诊断出的650万癌症患者的数据。经过质量检查的条目详细说明了年龄、性别、诊断日期、癌症部位、形态学、显微镜检查和生命状态，并包含了广泛的分期指标。对于EUROCARE-3，指的是1990年至1994年的诊断，3389例有重大数据问题的病例和142 525例继发性或继发性癌症被删除，留下200多万例病例供分析。根据这些数据，计算每个癌症部位和国家在诊断后1年、3年和5年的观察生存率和相对生存率。每个癌症部位和所有癌症合并后的欧洲总体生存率结合国家特定生存率数据进行计算。总体而言，1.1%的病例因随访而丢失，4.2%仅从死亡证明中得知，1.2%仅在尸检中得知。显微镜下确诊病例的百分比因癌症部位和国家而异，北欧国家总是较高。EUROCARE-3数据库的质量指标与早期EUROCARE数据库的比较表明，数据质量和标准化有所提高。
The EUROCARE database contains data on 6.5 million cancer patients diagnosed from 1978 to 1994 in populations covered by 67 cancer registries in 22 European countries. The quality-checked entries specify age, sex, diagnosis date, cancer site, morphology, microscopic confirmation and vital status, as well as containing broad indicators of stage. For EUROCARE-3, which refers to diagnoses from 1990 to 1994, 3389 cases with major data problems and 142 525 second or subsequent cancers were removed, leaving more than 2 million cases for analysis. From these data, observed and relative survival for each cancer site and country were calculated at 1, 3 and 5 years from diagnosis. Overall European survival for each cancer site and for all cancers combined were calculated combining country-specific survival figures. Overall, 1.1% of cases were lost to follow-up, 4.2% were known from death certificates only and 1.2% were known at autopsy only. The percentage of microscopically confirmed cases varied with cancer site and country, and was always higher in northern European countries. Comparison of quality indicators for the EUROCARE-3 database with earlier EUROCARE databases indicates that data quality and standardisation have improved.