Predictors of surgical outcome in thoracic spinal stenosis: Focusing on cerebrospinal fluid leakage
Predictors of surgical outcome in thoracic spinal stenosis: Focusing on cerebrospinal fluid leakage
复制标题
胸椎管狭窄症手术结果的预测因素：关注脑脊液漏
DOI：
10.1016/j.jksus.2020.04.008
复制
发表时间：
2020
期刊：
影响因子：
--
通讯作者：
X. Liu
中科院分区：
文献类型：
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作者：
Lei Wang;X. Liu;Zhongjun Liu;F. Wei;Liang Jiang;Miao Yu;X. Liu
The study was designed to investigate the effect of cerebrospinal fluid leakage (CFSL) on the surgical outcomes of thoracic spinal stenosis (TSS). 153 TSS cases were recruited for this study from January 2012 to December 2017. Preoperative duration of symptoms, neurological status, operative parameters, postoperative courses and neurological recovery were collected. Modified Japanese Orthopedic Association (JOA) score for thoracic myelopathy was used to assess neurological status, and recovery rate was calculated, accordingly. Comparison was between postoperative transient neurological deterioration (PTND) group and Non-PTND group. Cases were further grouped into favorable outcome (FO) (JOA recovery rate ≥25%) and unfavorable outcome (UO) (JOA recovery rate <25%) group, respectively. Further, multivariate logistic regression was performed to verify their relationships. Result showed that seventeen patients (11.1%) developed PTND, while sixty-seven patients (43.8%) developed CSFL. The mean JOA recovery rate was 58.2 ± 35.3%. The incidence of CSFL in PTND group was significantly lower than that in non-PTND group (17.65% vs 47.06%,p= 0.02). Multiple regression analysis showed that CSFL indicated a lower incidence of PTND (B = 1.608,p= 0.03). However, there was no significant difference between the incidence of CSFL in FO group and that of UO group (27.28% vs 46.56%, p = 0.09). In addition, preoperative duration of symptoms, preoperative JOA score and blood loss were associated with the surgical outcomes. The present study found that CSFL was associated with a lower risk of PTND in TSS, which has a certain guiding significance for clinical surgery.
DOI：
10.1016/j.ymeth.2020.02.002
发表时间：
2020-05-01
期刊：
Methods (San Diego, Calif.)
影响因子：
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作者：
Muraoka S;Lin W;Chen M;Hersh SW;Emili A;Xia W;Ikezu T
通讯作者：
Ikezu T