Physical and light oxidative properties of eugenol encapsulated by molecular inclusion and emulsion-diffusion method
Physical and light oxidative properties of eugenol encapsulated by molecular inclusion and emulsion-diffusion method
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DOI：
10.1016/j.foodres.2008.09.011
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发表时间：
2009-01-01
影响因子：
8.1
通讯作者：
Ruktanonchai, Uracha
中科院分区：
文献类型：
--
作者：
Choi, Mi-Jung;Soottitantawat, Apinan;Ruktanonchai, Uracha
本研究的目的是研究丁香酚作为一种挥发性活性物质包合与β-环糊精（β-CD）和2-羟丙基-β-环糊精（2-HP-β-CD），并通过乳化扩散法与聚己内酯（PCL）的包合。在配制每种类型的复合物之后，通过使用Nanosizer（R）、差示扫描量热法（DSC）和热重分析（TGA）、透射电子显微镜（TEM）、扫描电子显微镜（SEM）和原子力显微镜（AFM）来确定尺寸、zeta电位和热性质。总体而言，包封的丁香酚的平均尺寸在320 nm处相同。然而，与用聚己内酯（PCL）包封的丁香酚相比，β-CD和2-HP-β-CD包合物的尺寸分布是多分散的。热重分析结果表明，PCL、β-CD丁香酚和2-HP-β-CD丁香酚包合物的包封率分别为100%、90.9%和89.1%。氧化稳定性研究表明，乳液扩散法比分子包合法更有效，因为稳定性取决于储存时间。另一方面，β-CD比2-HP-β-CD更有效地包封丁香酚。推测2-HP-β-CD的羟丙基侧链可能会中断丁香酚包合在2-HP-β-CD分子的空腔内。从我们的实验中，我们得出结论，乳化扩散法是丁香酚包封在储存期间最有效的保护，因为从TEM分析，它们完全被PCL层包裹。(C)2008爱思唯尔有限公司保留所有权利。
The aim of this research was to study the encapsulation of eugenol as a volatile active substance by inclusion with beta-cyclodextrin (beta-CD) and 2-hydroxypropyl-beta-cyclodextrin (2-HP-beta-CD), and by an emulsion-diffusion method with polycaprolactone (PCL). After formulation of each type of complex, size, zetapotential, and thermal properties were determined by using Nanosizer (R), differential scanning calorimetry (DSC), and thermogravimetric analysis (TGA), transmission electron microscopy (TEM), scanning electron microscopy (SEM), and atomic force microscopy (AFM). Overall, the mean sizes of encapsulated eugenol were the same at 320 nm. However, the size distribution of the beta-CD and 2-HP-beta-CD inclusion complex was poly-disperse as compared with eugenol encapsulated with polycaprolactone (PCL). TGA analysis revealed the encapsulation efficiency of PCL, beta-CD eugenol and 2-HP-beta-CD eugenol inclusion complexes were 100%, 90.9% and 89.1 %, respectively. The study of oxidation stability revealed the emulsion-diffusion method was more efficient than the molecular inclusion method resulting from high stability depending on storage time. On the other hand, beta-CD was more effective than 2-HP-beta-CD for eugenol encapsulation. It is supposed that the side chain of hydroxypropyl group of 2-HP-beta-CD might interrupt eugenol inclusion within the cavity of 2-HP-beta-CD molecule, From our experiments, we concluded that the emulsion-diffusion method was the most effective for eugenol encapsulation to protect from light oxidation during storage time due to their complete wrapping of eugenol by PCL layer from TEM analysis. (C) 2008 Elsevier Ltd. All rights reserved.