Ancestral inbreeding only minimally affects inbreeding depression in mammalian populations
Ancestral inbreeding only minimally affects inbreeding depression in mammalian populations
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DOI：
10.1093/oxfordjournals.jhered.a023085
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发表时间：
1997-05-01
影响因子：
3.1
通讯作者：
Ballou, JD
中科院分区：
文献类型：
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作者：
Ballou, JD
通过对有害等位基因的选择，可以减少或消除近交抑制。这一预测是建议将患有近交抑制的圈养野生动物种群有意地从健康的近交动物中繁殖出来的基础。然而，关于清除近亲繁殖抑郁的有效性的数据很少。在本研究中，我提出并使用了两种不同的回归模型（祖先近交模型和致死隐性模型）来测试25个圈养哺乳动物种群中清除效应的存在，检查的适应度成分是新生儿存活率，从新生儿到断奶的存活率和产仔数，只有一个物种的清除在统计上显着，然而，近交抑制的17个物种中有15个在近交动物后代的新生儿存活率中表现出轻微的近交抑制。这些结果显示了一个小但非常显著的趋势清洗新生儿存活率。在断奶存活率或产仔数方面没有观察到清除效应的趋势，这种效应不太可能强到足以在消除近交抑制方面有实际应用。
Inbreeding depression can be reduced, or purged, by selection against deleterious alleles, This prediction is the basis of the recommendation that captive wildlife populations suffering from inbreeding depression be intentionally bred from healthy inbred animals. Yet data on the effectiveness of purging inbreeding depression are few. In this study I present and use two different regression models (an ancestral inbreeding model and a lethal recessive model) to test for the presence of purging effects in 25 captive mammalian populations, Fitness components examined were neonatal survival, survival from neonate to weaning, and litter size, In only one species was purging statistically significant, However, 15 of 17 species that showed inbreeding depression exhibited a slight decline in inbreeding depression in neonatal survival among descendants of inbred animals. These results show a small but highly significant trend of purging on neonatal survival. No trends in purging effects were observed in weaning survival or litter size, The effects were not likely to be strong enough to be of practical use in eliminating inbreeding depression.