Alcohol consumption before sleep is associated with severity of sleep-disordered breathing among professional Japanese truck drivers
Alcohol consumption before sleep is associated with severity of sleep-disordered breathing among professional Japanese truck drivers
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DOI：
10.1111/j.1530-0277.2007.00538.x
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发表时间：
2007-12-01
影响因子：
3.2
通讯作者：
Iso, Hiroyasu
中科院分区：
文献类型：
--
作者：
Sakurai, Susumu;Cui, Renzhe;Iso, Hiroyasu
背景：已知饮酒和超重会加重睡眠呼吸障碍（SDB）的严重程度，但对卡车司机的饮酒知之甚少。本研究旨在探讨卡车司机饮酒与SDB之间的关系。方法：我们对1465名在日本卡车运输协会注册的20-69岁男性进行了横断面研究。选择3%氧去饱和指数（3% odi）作为SDB的指标，表示在夜间脉搏血氧仪的基础上，记录时间内每小时血氧下降>= 3%的去饱和事件数。参与者在同一天晚上完成了一份自我管理的问卷，包括酒精摄入量，以评估SDB。结果：3%ODI >= 5、>= 10、>= 15/h的患病率分别为25.4%、11.1%、6.6%。与不饮酒者相比，3%ODI >= 10/h的多变量优势比（OR）为0.5至< 1.0 g酒精摄入量/kg时为1.5(0.9-2.5),>= 1.0 g酒精摄入量/kg时为3.4（1.8-6.6）。在3%ODI >= 5和>= 15/h时，也观察到与酒精消费量相似的关联。在体重指数(BMI) < 23.4 kg/m(2)的男性中，酒精摄入量（>= 1.0 g/ kg）与3%ODI >= 10/h之间的关系比BMI = 23.4 kg/m(2)的男性更为明显[11.4（3.2-41）比1.2(0.6-2.7)，相互作用p = 0.18]。3%ODI >= 5/h时也有类似的趋势。结论：未确诊的SDB患病率以及饮酒与SDB严重程度的显著相关性，强调了对卡车司机进行SDB筛查、酒精改造和体重控制以预防和控制SDB的必要性。
Background: Alcohol consumption as well as overweight is known to aggravate the severity of sleep-disordered breathing (SDB), but little is known about alcohol consumption in truck drivers. The aim of this study was to examine the relationship between alcohol consumption and SDB among truck drivers.Methods: We conducted a cross-sectional study of 1,465 men aged 20-69 years who were registered with the Japanese Trucking Association. The 3% oxygen desaturation index (3%ODI) was selected as an indicator of SDB, representing the number of desaturation events per hour of recording time in which blood oxygen fell by >= 3% based on overnight pulse-oximetry. Participants completed a self-administered questionnaire including alcohol consumption on the same night for SDB assessment.Results: The prevalence of 3%ODI >= 5, >= 10, and >= 15/h was 25.4%, 11.1%, and 6.6% respectively. The multivariable odds ratios (OR) of 3%ODI >= 10/h were 1.5(0.9-2.5) for 0.5 to < 1.0 g of alcohol intake/kg and 3.4(1.8-6.6) for >= 1.0 g of alcohol intake/kg compared with non-drinkers. Similar associations with alcohol consumption were observed for 3%ODI >= 5 and >= 15/h. The relation between alcohol consumption (>= 1.0 g of alcohol intake/kg) and 3%ODI >= 10/h tended to be more evident among men with body mass index (BMI) < 23.4 kg/m(2) than those with BMI >= 23.4 kg/m(2) [11.4 (3.2-41) vs. 1.2 (0.6-2.7), p = 0.18 for interaction]. A similar trend was observed for 3%ODI >= 5/h.Conclusion: The prevalence of undiagnosed SDB and the significant association of alcohol consumption with SDB severity emphasize the need for SDB screening and alcohol modification as well as weight control to prevent and control SDB among truck drivers.