Functional Connectivity of the Dorsal Striatum in Female Musicians.
Functional Connectivity of the Dorsal Striatum in Female Musicians.
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DOI：
10.3389/fnhum.2016.00178
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发表时间：
2016
影响因子：
2.9
通讯作者：
Kirino E
中科院分区：
文献类型：
--
作者：
Tanaka S;Kirino E
背侧纹状体（尾状核/壳核）是皮质-纹状体-苍白球-丘脑-皮质（CSPTC）运动回路的一个节点，在熟练的运动学习中起着核心作用，这是音乐表演的一个关键特征。背侧纹状体接收来自大部分大脑皮层的输入，形成皮层-皮层下网络的枢纽。这项研究旨在研究背侧纹状体的功能网络在音乐家和非音乐家之间的差异。静息态功能磁共振成像（fMRI）数据采集的女大学生主修音乐和非音乐学科。数据进行了功能连接性分析和图论分析。功能连接分析表明，与非音乐家相比，音乐家的左壳核和双侧额盖（FO）之间以及左尾状核和小脑之间的连接显着减少。对整个大脑的图论分析显示，音乐家的双侧壳核的度数（代表连接的数量）明显低于非音乐家。总之，与非音乐家相比，女性音乐家有一个较小的功能网络的背侧纹状体连接减少。这些数据与以前的解剖学研究报告的音乐家和芭蕾舞演员的背侧纹状体体积减少是一致的，这表明长期的音乐训练重塑了背侧纹状体的功能网络，使其不那么广泛或选择性。
The dorsal striatum (caudate/putamen) is a node of the cortico-striato-pallido-thalamo-cortical (CSPTC) motor circuit, which plays a central role in skilled motor learning, a critical feature of musical performance. The dorsal striatum receives input from a large part of the cerebral cortex, forming a hub in the cortical-subcortical network. This study sought to examine how the functional network of the dorsal striatum differs between musicians and nonmusicians. Resting state functional magnetic resonance imaging (fMRI) data were acquired from female university students majoring in music and nonmusic disciplines. The data were subjected to functional connectivity analysis and graph theoretical analysis. The functional connectivity analysis indicated that compared with nonmusicians, musicians had significantly decreased connectivity between the left putamen and bilateral frontal operculum (FO) and between the left caudate nucleus and cerebellum. The graph theoretical analysis of the entire brain revealed that the degrees, which represent the numbers of connections, of the bilateral putamen were significantly lower in musicians than in nonmusicians. In conclusion, compared with nonmusicians, female musicians have a smaller functional network of the dorsal striatum with decreased connectivity. These data are consistent with previous anatomical studies reporting a reduced volume of the dorsal striatum in musicians and ballet dancers, suggesting that long-term musical training reshapes the functional network of the dorsal striatum to be less extensive or selective.