Insulin increases thermogenesis in rat skeletal muscle following exercise.
Insulin increases thermogenesis in rat skeletal muscle following exercise.
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胰岛素增加运动后大鼠骨骼肌的生热作用。
DOI：
10.1152/ajpendo.1985.248.1.e148
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发表时间：
1985
期刊：
影响因子：
--
通讯作者：
Ruderman,NB
中科院分区：
文献类型：
--
作者：
Balon,TW;Zorzano,A;Goodman,MN;Ruderman,NB
在跑步机跑后2小时以上，胰岛素可增加离体灌流的大鼠肌肉的耗氧量。胰岛素不会增加非运动大鼠的耗氧量，在没有添加胰岛素的情况下，先前的运动也不会增加耗氧量。运动前大鼠肌肉中胰岛素对糖原合成的刺激作用也有所增强。然而，这需要的额外能量不足以解释氧气消耗的增加。结果表明，胰岛素增加了运动后骨骼肌的生热作用。他们还提出了这样一种可能性，即在完整的生物体中，增加胰岛素分泌的食物的生热效应可能会通过事先的锻炼而增加。
Insulin increased O2 consumption in isolated perfused rat muscle for upward of 2 h after a treadmill run. Insulin did not increase O2 consumption in nonexercised rats, nor did prior exercise increase O2 consumption in the absence of added insulin. The stimulation of glycogen synthesis by insulin was also enhanced in muscle of previously exercised rats. The additional energy required for this was not sufficient to account for the increase in O2 consumption, however. The results indicate that insulin increases thermogenesis in skeletal muscle after exercise. They also raise the possibility that in intact organisms the thermogenic effect of foods that increase insulin secretion could be increased by prior exercise.