Opportunities for penicillin allergy evaluation in dental clinics.
Opportunities for penicillin allergy evaluation in dental clinics.
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DOI：
10.1017/ash.2022.18
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发表时间：
2022
期刊：
影响因子：
--
通讯作者：
Suda, Katie J
中科院分区：
文献类型：
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作者：
Vivo, Amanda;Durkin, Michael J;Kale, Ibuola;Boyer, Taylor;Fitzpatrick, Margaret A;Evans, Charlesnika T;Jurasic, M Marianne;Gibson, Gretchen;Suda, Katie J
评估评估就诊于牙科诊所的患者青霉素过敏的机会。回顾性横断面研究。弗吉尼亚州牙科诊所。研究对象包括有青霉素过敏史并在 2015 年 1 月 1 日至 2018 年 12 月 31 日期间从牙医处接受抗生素治疗的成年患者。对 100 名接受非头孢菌素抗生素治疗的患者和 200 名接受头孢菌素治疗的患者的随机样本完成了图表审查。每种过敏都按严重程度进行分类。这些类别用于根据同行评审的算法确定患者是否有资格参加 3 个测试组：(1) 不进行测试，(2) 皮肤测试，以及 (3) 口服测试剂量挑战。首先使用描述性和双变量统计数据来比较设施和患者的人口统计数据，包括真正的青霉素过敏、假性青霉素过敏和缺失的过敏记录，以及在牙科就诊时接受头孢菌素治疗的患者和未接受头孢菌素治疗的患者。总体而言，19% 的人缺乏过敏反应性质的记录，53% 的人有资格进行皮肤测试，27% 的人有资格进行口服测试剂量挑战，1% 的人禁止进行测试。男性患者和非裔美国患者接受头孢菌素治疗的可能性较小。退伍军人管理局接受牙医抗生素治疗的大多数青霉素过敏患者都有资格接受青霉素皮试或口服青霉素挑战。需要进一步的研究来了解牙医和牙科诊所在评估青霉素过敏方面的作用。
To evaluate opportunities for assessing penicillin allergies among patients presenting to dental clinics. Retrospective cross-sectional study. VA dental clinics. Adult patients with a documented penicillin allergy who received an antibiotic from a dentist between January 1, 2015, and December 31, 2018, were included. Chart reviews were completed on random samples of 100 patients who received a noncephalosporin antibiotic and 200 patients who received a cephalosporin. Each allergy was categorized by severity. These categories were used to determine patient eligibility for 3 testing groups based on peer-reviewed algorithms: (1) no testing, (2) skin testing, and (3) oral test-dose challenge. Descriptive and bivariate statistics were used to compare facility and patient demographics first between true penicillin allergy, pseudo penicillin allergy, and missing allergy documentation, and between those who received a cephalosporin and those who did not at the dental visit. Overall, 19% lacked documentation of the nature of allergic reaction, 53% were eligible for skin testing, 27% were eligible for an oral test-dose challenge, and 1% were contraindicated from testing. Male patients and African American patients were less likely to receive a cephalosporin. Most penicillin-allergic patients in the VA receiving an antibiotic from a dentist are eligible for penicillin skin testing or an oral penicillin challenge. Further research is needed to understand the role of dentists and dental clinics in assessing penicillin allergies.