Reduced variance of latencies in pudendal evoked potentials after normalization for body height
Reduced variance of latencies in pudendal evoked potentials after normalization for body height
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DOI：
10.1002/nau.1930140305
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发表时间：
1995
影响因子：
2
通讯作者：
G. Nikiforidis;Constantinos Koutsojannis;S. Giannoulis;G. Barbalias
中科院分区：
文献类型：
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作者：
G. Nikiforidis;Constantinos Koutsojannis;S. Giannoulis;G. Barbalias
如果体感诱发电位(SEP)特征参数的标准标准化，并考虑到所有其他系统变异源，则体感诱发电位(SEP)在神经疾病评估和检测中的价值将显著提高。本研究探讨了身高对阴部体感诱发电位的峰潜伏期和峰间潜伏期的影响。本文对40例男性正常人(年龄20~40岁)的L1椎体诱发电位峰值潜伏期(L1)和刺激阴部神经后皮质诱发电位的起始潜伏期(ONC)与身高的关系进行了研究。ONC潜伏期与ONC-L1峰间潜伏期和身高呈显著正相关。假设后者与神经通路的长度成正比，实验数据使用了一个理论模型进行拟合，该模型表示感觉神经轴的传导是身高的函数。使用估计的拟合函数，我们对关于典型身高的数据进行了归一化。与原始潜伏期相比，上述潜伏期的归一化值方差显著减小，因此它们的诊断重要性显著增加。对L1(脊柱)潜伏期和球海绵体肌反射潜伏期(BCR)的类似程序显示与身高无关，这是基于神经解剖学的考虑而讨论的。©1995 Wiley-Liss公司
The value of the Somatosensory Evoked Potentials (SEP) in the assessment and detection of neurological disorders could be considerably enhanced if the normative standards of (SEP) characteristic parameters were normalized taking into account all other systematic sources of variance. The present study examines the influence of body height on the peak and interpeak latencies of the pudendal somatosensory evoked potentials. We examined the peak latency (L1) of the evoked potential recorded at the L1 vertebra and the onset latency (ONc) of the cortical evoked potentials, after stimulation of the pudendal nerve, as a function of body height in 40 normal male subjects (age 20–40 years). Significant positive correlation was found between both (ONc) latency and ONc‐L1 interpeak latency and body height (H). Assuming that the latter is proportional to the length of the neural pathways, the experimental data were fitted using a theoretical model representing the conduction in the sensory neuraxis as a function of body height. Using the estimated fitting functions, we normalized our data with regard to a typical value of body height. The normalized values of the aforementioned latencies reveal a significantly reduced variance, as compared to the original ones, and consequently their diagnostic importance is significantly increased. Similar procedures applied to the L1 (spinal) latencies and the latencies of the bulbocavernosus reflex (BCR) reveal no correlation with body height and this is discussed on the basis of neuroanatomical considerations. © 1995 Wiley‐Liss, Inc.