Short chain fatty acids present in periodontal pockets may play a role in human periodontal diseases.
Short chain fatty acids present in periodontal pockets may play a role in human periodontal diseases.
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DOI：
10.1111/j.1600-0765.1987.tb01565.x
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发表时间：
1987-05
影响因子：
3.5
通讯作者：
M. Tonetti;C. Eftimiadi;G. Damiani;P. Buffa;D. Buffa;G. Botta
中科院分区：
文献类型：
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作者：
M. Tonetti;C. Eftimiadi;G. Damiani;P. Buffa;D. Buffa;G. Botta
牙周袋中的短链脂肪酸（SCFA）可能在人类牙周疾病中发挥作用。早期的报告表明，SCFA可以渗透口腔粘膜，因为目前认为结合上皮对各种化合物具有高度渗透性，并且SCFA的特征可能在于存在极性和非极性基团。可以假定SCFA可以从龈下菌斑扩散到牙周组织中，从而导致对牙周组织的潜在破坏作用。
Short chain fatty acids (SCFA) present in periodontal pockets may play a role in human periodontal diseases. An early report has indicated that SCFA may penetrate oral mucosa, since junctional epithelium is presently considered to be highly permeable to a wide range of compounds, and since SCFA may be pharmacologically characterized by the presence of both polar and non-polar groups. it may be postulated that SCFA may diffuse from subgingival plaque in to periodontal tissues, thus leading the way to potentially damaging effects on the periodontium.