Chemo-, regio-, and stereo-selective perfluoroalkylations by a Grignard complex with zirconocene.
Chemo-, regio-, and stereo-selective perfluoroalkylations by a Grignard complex with zirconocene.
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通过格氏配合物与二茂锆进行化学、区域和立体选择性全氟烷基化。
DOI：
10.1039/c5dt03039k
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发表时间：
2015
影响因子：
4
通讯作者：
K. Mikami
中科院分区：
文献类型：
--
作者：
Motohiro Fujiu;Kazuyuki Negishi;J. Guang;P. Williard;S. Kuroki;K. Mikami
报道了高活性全氟烷基格氏试剂与早过渡金属茂锆络合物的合成及其与环氧化物的新型高化学、区域和立体选择性的全氟烷基化反应。新锆络合物有利于活化全氟烷基格氏物种。用DOSY分析了新锆格氏络合物的结构。~(1)H和~(19)F剂量分析表明，MAO和二氧六环加入到RfMgCl2和Cp2ZrCl2的混合物中，连接了Cp2Zr和RfMg，生成了二氧六环/全氟烷-格氏络合物。
The synthesis of highly reactive perfluoroalkyl Grignard reagents with early transition metal zirconocene complexes and their new types of highly chemo-, regio-, and stereo-selective perfluoroalkylation reactions are reported with epoxides in particular. The zirconocene complex is advantageous in activating the perfluoroalkyl Grignard species. The zirconocene·Grignard complexes were clarified by DOSY. Both (1)H and (19)F DOSY analyses show that the addition of MAO and dioxane to the mixture of RFMgCl and Cp2ZrCl2 connects Cp2Zr and RFMg to generate the zirconocene/perfluoroalkyl-Grignard/dioxane complex.
影响因子：
15
作者：
Li D;Kagan G;Hopson R;Williard PG
通讯作者：
Williard PG
影响因子：
18.3
作者：
Li, Deyu;Keresztes, Ivan;Hopson, Russell;Williard, Paul G.
通讯作者：
Williard, Paul G.