Congenital Nasopharyngeal Teratoma with a Cleft Palate: Case Report and a 7 Year Follow Up
Congenital Nasopharyngeal Teratoma with a Cleft Palate: Case Report and a 7 Year Follow Up
复制标题
DOI：
10.1007/s12663-010-0140-6
复制
发表时间：
2011-09-01
影响因子：
0.9
通讯作者：
Inderchand, Singhvi
中科院分区：
文献类型：
--
作者：
Chauhan, Dinesh Singh;Guruprasad, Yadavalli;Inderchand, Singhvi
畸胎瘤是一种含有外胚层、中胚层和内胚层细胞的良性肿瘤。每4,000名新生儿中就有1名发生这种情况，最常见的是在骶尾部，其次是卵巢。先天性内膜畸胎瘤是一种罕见的位于头颈部的胚胎性肿瘤。在大约1：35,000-1：200,000的活产儿中发现了一个附着点。这占所有畸胎瘤的2-9%。口鼻咽部肿瘤的大小和位置各不相同。畸胎瘤在出生时部分未被诊断出来。它们可能存在于颅内或以小息肉的形式存在。巨大的胎膜肥大可能会导致产中和产后处理困难。我们报告一位女性婴儿合并鼻咽畸胎瘤及腭裂的病例，并通过分期手术方式成功地进行了多学科的治疗。上颌骨表现为一个巨大的肿块，从女婴的嘴里伸出来。在出生当天，肿瘤的口外部分被剥离，随后进行口腔内摘除和后来的腭裂修复。组织病理学检查结果证实诊断为先天性畸胎瘤。
Teratomas are benign tumors containing cells from ectodermal, mesodermal and endodermal layers. They occur in about 1 in every 4,000 births and most commonly in the sacrococcygeal region, followed by the ovaries. Congenital epignathus teratomas are rare embryological neoplasms localised in the region of head and neck. An epignathus is found in approximately 1:35,000-1:200,000 live births. This accounts for 2-9% of all teratomas. Size and location of the neoplasm in the oronasopharynx is variable. Teratomas are partly undiagnosed at the time of birth. They may exist with an intracranial extension or as small polyps. Large epignathi can lead to difficult management during and after birth. We present a case of a female infant with a combination of nasopharyngeal teratoma and a cleft palate with successful multidisciplinary management via a staged surgical approach. The epignathus presented as a huge mass extending out of the mouth of the infant girl. On the day of birth debulking of the extraoral portion of the tumor, followed by intraoral extirpation and cleft palate repair at a later stage, was performed. The results of the histopathological examination confirmed diagnosis of a congenital teratoma.