Evaluation of the CO2 Rebreathing Cardiac Output Method In Seriously III Patients

Evaluation of the CO2 Rebreathing Cardiac Output Method In Seriously III Patients
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CO2 再呼吸心输出量法在重症 III 期患者中的评价

DOI:
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发表时间:
1977
期刊:
影响因子:
37.8
通讯作者:
J. Franciosa
J. Franciosa
中科院分区:
医学1区
文献类型:
--
作者:
J. Franciosa

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CO2再呼吸心输出量方法是一种完全无创的Fick程序,需要在各种疾病状态下进行验证,才能在临床上适用。同时测量心输出量的二氧化碳再呼吸和染料稀释或直接菲克技术进行了53例。在9例肺部疾病患者中,再呼吸心输出量平均为4.85 L/min,而染料稀释法或Fick法为5.18 L/min(r = 0.16)。14例急性心肌梗塞患者的心输出量,再呼吸法为5.53 L/min,染料稀释法为5.87 L/min(r = 0.95); 9例休克患者的心输出量,染料稀释法或Fick法为3.98 L/min,CO2再呼吸法为3.75 L/min(r = 0.94)。在5例二尖瓣关闭不全的心力衰竭病例中,标准方法与再呼吸方法之间的相关性为r = 0.09,而在16例无二尖瓣返流的病例中,r = 0.89。10例患者的急性干预使染料稀释心输出量增加0.92 L/min,再呼吸输出量增加0.60 L/min(r = 0.87)。这些数据表明,CO2再呼吸心输出量方法可能是有用的CCU-MICU设置。
The CO2 rebreathing cardiac output method is a totally noninvasive Fick procedure needing validation in various disease states to become clinically applicable. Simultaneous measurements of cardiac output by CO2 rebreathing and dye-dilution or direct Fick techniques were performed in 53 patients. In nine patients with pulmonary disease rebreathing cardiac output averaged 4.85 L/min compared to 5.18 L/min by dye-dilution or Fick (r = 0.16). In 14 instances of acute myocardial infarction cardiac output was 5.53 L/min by rebreathing and 5.87 L/min by dye-dilution (r = 0.95), while in nine shock cases it averaged 3.98 L/min by dye-dilution or Fick and 3.75 L/min by CO2 rebreathing (r = 0.94). In five heart failure cases with mitral insufficiency, which may distort dye curves, correlation between standard and rebreathing methods was r = 0.09, but in 16 cases without mitral regurgitation, r = 0.89. Acute interventions in ten patients increased dye-dilution cardiac output by 0.92 L/min and rebreathing outputs by 0.60 L/min (r = 0.87). The data suggest that the CO2 rebreathing cardiac output method may be useful in the CCU-MICU setting.