Focal nerve enlargement is not the cause for increased distal motor latency in ALS: Sonographic evaluation
Focal nerve enlargement is not the cause for increased distal motor latency in ALS: Sonographic evaluation
复制标题
局灶神经增大并不是 ALS 远端运动潜伏期增加的原因：超声评估
DOI：
10.1016/j.clinph.2014.10.152
复制
发表时间：
2015
影响因子：
4.7
通讯作者：
R. Kaji
中科院分区：
文献类型：
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作者：
A. Mori;H. Nodera;N. Takamatsu;Y. Shimatani;K. Maruyama;M. Oda;Y. Izumi;R. Kaji
目的探讨肌萎缩侧索硬化症(ALS)患者正中神经局灶性传导减慢的机制。方法对ALS和CTS患者及正常对照组进行正中神经和尺神经超声检查。结果ALS和CTS患者的正中运动远端潜伏期明显延长。肌萎缩侧索硬化症患者正中神经的CSA和腕前臂比值均小于CTS患者。结论肌萎缩侧索硬化症患者腕部正中神经选择性传导减慢不太可能是继发性压迫性神经病所致，如腕管综合征所见。
ObjectiveTo elucidate the mechanism of focal conduction slowing in the median nerve in ALS.MethodsThe patients with ALS and CTS and normal control subjects were tested with sonography of the median and ulnar nerves. The cross-sectional areas (CSAs) and the wrist–forearm CSA ratios were compared with the parameters of nerve conduction study.ResultsThe median motor distal latency was frequently prolonged in ALS and CTS. CSA and the wrist–forearm ratio of the median nerve were smaller in ALS than in CTS. The ulnar nerve sonography was similar in all the groups.ConclusionsSelective conduction slowing of the median nerve at the wrist in ALS is unlikely due to secondary compressive neuropathy, as seen in carpal tunnel syndrome.SignificanceUnique vulnerability of the median nerve in ALS may explain the selective conduction slowing.
Kaji R：“多灶性运动神经病和其他脱髓鞘性神经病中传导阻滞的生理学”肌肉神经.. 27(3)。
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