STORM: software for testing hypotheses of relatedness and mating patterns

STORM: software for testing hypotheses of relatedness and mating patterns
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DOI:
10.1111/j.1755-0998.2008.02358.x
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发表时间:
2008-11-01
影响因子:
7.7
通讯作者:
Frasier, Timothy R.
Frasier, Timothy R.
中科院分区:
生物学1区
文献类型:
--
作者:
Frasier, Timothy R.

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Storm是一个软件包,允许用户测试有关群体内相关性模式和配偶选择模式和/或配偶相容性的各种假设。这些功能基于四个主要的计算,可以独立进行,也可以在假设检验框架中进行:内部相关性;基因座纯合性;成对相关性;以及一个称为等位基因遗传的新指标,该指标计算后代继承的父亲等位基因与从母亲继承的等位基因不同的基因座比例。STORM允许用户基于这些计算和蒙特卡罗模拟来测试四个假设:(i)观察到的关联或分组中的个体是否比预期更相关/更不相关;(ii)观察到的后代是否具有更多/更少的遗传变异性(基于基因座的内部相关性或纯合性)比从基因库预期的高;(iii)如果交配在相关性方面是随机的,则观察到的交配对比预期的更相关/更不相关;和(iv)观察到的后代是否比基于孟德尔遗传的预期更经常/更不经常地遗传不同于从母亲遗传的那些的父系等位基因。
Storm is a software package that allows users to test a variety of hypotheses regarding patterns of relatedness and patterns of mate choice and/or mate compatibility within a population. These functions are based on four main calculations that can be conducted either independently or in the hypothesis-testing framework: internal relatedness; homozygosity by loci; pairwise relatedness; and a new metric called allele inheritance, which calculates the proportion of loci at which an offspring inherits a paternal allele different from that inherited from its mother. STORM allows users to test four hypotheses based on these calculations and Monte Carlo simulations: (i) are individuals within observed associations or groupings more/less related than expected; (ii) do observed offspring have more/less genetic variability (based on internal relatedness or homozygosity by loci) than expected from the gene pool; (iii) are observed mating pairs more/less related than expected if mating is random with respect to relatedness; and (iv) do observed offspring inherit paternal alleles different from those inherited from the mother more/less often than expected based on Mendelian inheritance.