The natural history of recurrent bacteriuria in schoolgirls.
The natural history of recurrent bacteriuria in schoolgirls.
复制标题
女学生复发性菌尿的自然史。
DOI：
10.1056/nejm197006252822601
复制
发表时间：
1970
期刊：
影响因子：
--
通讯作者：
C. Kunin
中科院分区：
文献类型：
--
作者：
C. Kunin
摘要对在学校调查中发现尿路感染的女孩进行了一项关于复发性菌尿的长期研究。在大多数情况下，管理仅限于短期，具体的化疗加上频繁的随访检查。80%的复发是由于再次感染新的微生物。每个疗程都使20%至25%的白色女孩和大约40%的黑人女孩获得长期缓解。种群中的复发率遵循对数衰减曲线，这表明年龄和种族的显着影响。社会经济地位和膀胱输尿管反流对复发率没有显著影响。女孩保持无感染的时间越长，复发的频率往往越低，但她们患菌尿症的风险仍然高于一般人群。结婚和怀孕是风险增加的时期。
Abstract A long-term study of recurrent bacteriuria was carried out in girls in whom urinary-tract infection was detected during school surveys. In most of them management was limited to short-term, specific chemotherapy coupled with frequent follow-up examinations. Eighty per cent of recurrences were due to reinfection with a new organism. Each course of therapy extracted 20 to 25 per cent of white and about 40 per cent of Negro girls into long-term remission. Recurrences in the population closely followed a logarithmic decay curve, which demonstrated the marked effect of age and race. Socioeconomic status and vesicoureteral reflux had no significant effect on recurrence rates. Recurrences tended to be less frequent the longer the girls remained free of infection, but they were still at higher risk of acquiring bacteriuria than the general population. Marriage and pregnancy were times of increased risk.