Asymmetric synthesis of L-azetidine-2-carboxylic acid and 3-substituted congeners - Conformationally constrained analogs of phenylalanine, naphthylalanine, and leucine
Asymmetric synthesis of L-azetidine-2-carboxylic acid and 3-substituted congeners - Conformationally constrained analogs of phenylalanine, naphthylalanine, and leucine
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DOI：
10.1016/s0960-894x(99)00218-8
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发表时间：
1999-05-17
影响因子：
2.7
通讯作者：
Maguire, R
中科院分区：
文献类型：
--
作者：
Hanessian, S;Bernstein, N;Maguire, R
在乙醛酸o -苄基肟的樟脑丹衍生物上，采用锌介导的烯丙基卤化物不对称加成法制备了对映纯l -叠氮啶-2-羧酸、(3R)-苯基、(3R)-萘基和(3S)-异丙基类似物。1999爱思唯尔科学有限公司版权所有。
Enantiopure L-azetidine-2-carboxylic acid, the (3R)-phenyl, (3R)-naphthyl and (3S)-isopropyl analogs were prepared based on a zinc-mediated asymmetric addition of allylic halides to the camphor sultam derivative of glyoxylic acid O-benzyl oxime. (C) 1999 Elsevier Science Ltd. All rights reserved.