THE UK WORKING PARTY DIAGNOSTIC-CRITERIA FOR ATOPIC-DERMATITIS .3. INDEPENDENT HOSPITAL VALIDATION
THE UK WORKING PARTY DIAGNOSTIC-CRITERIA FOR ATOPIC-DERMATITIS .3. INDEPENDENT HOSPITAL VALIDATION
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DOI：
10.1111/j.1365-2133.1994.tb08532.x
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发表时间：
1994-09-01
影响因子：
10.3
通讯作者：
HAY, RJ
中科院分区：
文献类型：
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作者：
WILLIAMS, HC;BURNEY, PGJ;HAY, RJ
为了符合特应性皮炎的条件，我们建议一个人有瘙痒的皮肤状况加上三个或更多的以下：弯曲参与的历史，哮喘/花粉热的历史，全身皮肤干燥的历史，皮疹的发病年龄在2岁以下，或可见的弯曲皮炎。当在200个连续的所有年龄的皮肤科门诊患者的独立样本中进行测试时，这种诊断标准的安排在对医生的诊断进行验证时达到了69%的灵敏度和96%的特异性。根据这第一次演习的结果，对标准的措辞进行了微小的修改，并对连续114名儿童参加门诊儿科皮肤病诊所的样本进行了测试。总体辨别力提高，灵敏度为85%，特异性为96%。简化标准易于使用，每位患者只需不到2分钟即可确定，并且不需要受试者脱衣服。这两项独立的验证研究表明，新提出的特应性皮炎标准在医院门诊患者中表现相当好。需要在社区和发展中国家进一步验证。
In order to qualify as a case of atopic dermatitis, we propose that an individual muse have an itchy skin condition plus three or more of the following: history of flexural involvement, a history of asthma/hay fever, a history of a generalized dry skin, onset of rash under the age of 2 years, or visible flexural dermatitis. When tested in an independent sample of 200 consecutive dermatology outpatients of all ages, this arrangement of the diagnostic criteria achieved 69% sensitivity and 96% specificity when validated against physician's diagnosis. Based on the findings of this first exercise, minor modifications in the wording of the criteria were undertaken, and these were tested on a sample of 114 consecutive children attending out-patient paediatric dermatology clinics. Overall discrimination improved, with a sensitivity of 85% and specificity of 96%. The simplified criteria are easy to use, take under 2 min per patient to ascertain, and do not require subjects to undress. These two independent validation studies suggest that the newly proposed criteria for atopic dermatitis perform reasonably well in hospital out-patient patients. Further validation in community settings and in developing countries is needed.