Superselective intra-arterial chemotherapy of advanced paranasal sinus tumors.
Superselective intra-arterial chemotherapy of advanced paranasal sinus tumors.
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晚期鼻窦肿瘤的超选择性动脉内化疗。
DOI：
10.1001/archotol.1989.01860280101026
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发表时间：
1989
期刊：
影响因子：
--
通讯作者：
Helmuth Goepfert
中科院分区：
文献类型：
--
作者：
YY Lee;I. Dimery;P. Tassel';Charles A. De Pena;J. Blacklock;Helmuth Goepfert
采用超选择性动脉插管联合全身化疗治疗晚期副鼻窦肿瘤24例，近期肿瘤有效率达91%，明显优于文献报道。8例患者因完全或接近完全缓解而绕开了颅面外科手术。使用同轴系统对上颌内动脉翼段进行重复、简单的插管是成功诱导化疗的基石。对于这种激进的引入化疗，严格的医疗状况筛查是强制性的。
Twenty-four patients with advanced paranasal sinus tumors were treated with combined superselective intra-arterial and systemic chemotherapy, yielding an immediate satisfactory tumor response rate of 91%, significantly better than previously reported. Eight patients had craniofacial surgery circumvented because of complete or near complete response. Repetitive uncomplicated catheterization of the pterygoid segment of the internal maxillary artery using a coaxial system is the cornerstone of successful induction chemotherapy. Strenuous screening of medical status is mandatory for this aggressive introduction chemotherapy.