INSULIN STIMULATES SYNTHESIS OF SOLUBLE-PROTEINS IN ISOLATED RAT HEPATOCYTES
INSULIN STIMULATES SYNTHESIS OF SOLUBLE-PROTEINS IN ISOLATED RAT HEPATOCYTES
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DOI：
10.1042/bj1900615
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发表时间：
1980-01-01
影响因子：
4.1
通讯作者：
HANSEN, RJ
中科院分区：
文献类型：
--
作者：
CLARK, RL;HANSEN, RJ
在细胞外Leu浓度为0.15~20.0 mM的条件下，测定细胞内[~3H]Leu对可溶性细胞蛋白的掺入。当细胞外亮氨酸浓度较高时，胰岛素对[~3H]Leu参入率有12-15%的刺激作用。显然，胰岛素会导致肝脏蛋白质合成的速度略有增加。
The incorporation of [3H]Leu into soluble cellular protein was measured in isolated hepatocytes at extracellular Leu concentrations from 0.15-20.0 mM. Insulin caused a 12-15% stimulation of [3H]Leu incorporation in the presence of high extracellular Leu concentrations. Apparently, insulin causes a small increase in the rate of hepatic protein synthesis.