Constraint-Induced Therapy Versus Dose-Matched Control Intervention to Improve Motor Ability, Basic/Extended Daily Functions, and Quality of Life in Stroke
Constraint-Induced Therapy Versus Dose-Matched Control Intervention to Improve Motor Ability, Basic/Extended Daily Functions, and Quality of Life in Stroke
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DOI：
10.1177/1545968308320642
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发表时间：
2009-02-01
影响因子：
4.2
通讯作者：
Hsu, Chen-jung
中科院分区：
文献类型：
--
作者：
Lin, Keh-chung;Wu, Ching-yi;Hsu, Chen-jung
背景。约束诱导运动疗法（CIT）改善中风后上肢功能的试验通常不包括积极治疗的对照组。目标。本研究比较了改良的CIT干预与剂量匹配的对照干预，后者包括限制受影响较小的手，并评估了运动和功能表现以及与健康相关的生活质量的差异。方法。这项两组随机对照试验，采用治疗前和治疗后措施，招募了32例首次中风发作后6至40个月内的患者（平均年龄55.7岁）。他们接受CIT（限制受影响较轻的肢体并结合受影响肢体的强化训练，每天2小时，每周5天，持续3周，在康复训练之外限制受影响较轻的手5小时）或同样时间的常规干预，包括手限制。结果测量为Fugl-Meyer评估、功能独立性测量、运动活动日志、诺丁汉日常生活扩展活动量表和卒中影响量表。结果。与对照组相比，CIT组在运动功能、功能独立水平、日常生活中延伸活动的流动性和治疗后与健康相关的生活质量方面表现出明显更好的表现。结论。这种形式的CIT的稳健效果在结果的各个方面都得到了证明，包括运动功能、基本和扩展功能能力以及生活质量。
Background. Trials of constraint-induced movement therapy (CIT) to improve upper extremity function after stroke have usually not included an actively treated control group. Objective. This study compared a modified CIT intervention with a dose-matched control intervention that included restraint of the less affected hand and assessed for differences in motor and functional performance and health-related quality of life. Methods. This 2-group randomized controlled trial, using pretreatment and posttreatment measures, enrolled 32 patients within 6 to 40 months after onset of a first stroke (mean age, 55.7 years). They received either CIT (restraint of the less affected limb combined with intensive training of the affected limb for 2 hours daily 5 days per week for 3 weeks and restraint of the less affected hand for 5 hours outside of the rehabilitation training) or a conventional intervention with hand restraint for the same duration. Outcome measures were the Fugl-Meyer Assessment, Functional Independence Measure, Motor Activity Log, Nottingham Extended Activities of Daily Living Scale, and Stroke Impact Scale. Results. Compared with the control group, the CIT group exhibited significantly better performance in motor function, level of functional independence, mobility of extended activities during daily life, and health-related quality of life after treatment. Conclusions. The robust effects of this form of CIT were demonstrated in various aspects of outcome, including motor function, basic and extended functional ability, and quality of life.