Studies on retinal blood flow. I. Estimation of human retinal blood flow by slit-lamp fluorophotometry.
Studies on retinal blood flow. I. Estimation of human retinal blood flow by slit-lamp fluorophotometry.
复制标题
视网膜血流的研究。
DOI：
10.1001/archopht.1978.03910050495022
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发表时间：
1978
影响因子：
--
通讯作者：
J. Lima
中科院分区：
文献类型：
--
作者：
J. Cunha;J. Lima
本文介绍了一种通过裂隙灯荧光光度法估算人体视网膜血流量的新直接方法。该装置基本上由一个改进的裂隙灯组成，其目镜包含两个连接到双光度检测系统的光纤探头。两条光纤都聚焦在视网膜动脉段上，并自动记录荧光素团的通过，并在校正后给出平均通过时间。荧光素血管造影可以确定所研究的动脉段的体积。健康个体上颞叶视网膜血流量的平均值为 4.2 +/- 0.5 微升/分钟。对贫血患者的研究表明，视网膜血流量增加了约 52%。除了使用隐形眼镜引起的眼内压略有增加之外，与该技术相关的潜在错误原因似乎并不重要。
This article describes a new direct method for estimation of human retinal blood flow by slit-lamp fluorophotometry. The apparatus consists fundamentally of a modified slit lamp with an eye piece containing two fiberoptic probes connected to a double photometric detection system. Both optic fibers are focused on a retinal arterial segment, and the passage of a fluorescein bolus is automatically registered, giving, after correction, the mean transit time. Fluorescein angiography allows the determination of the volume of the arterial segment under study. Values for superior temporal retinal blood flow in healthy individuals show a mean value of 4.2 +/- 0.5 microliter/min. Studies in anemic patients show an increase of approximately 52% in the retinal blood flow. The potential causes of error associated with this technique, apart from the slight increase in intraocular pressure induced by the contact lens used, do not appear to be significant.