Caveats for the Use of Operational Electronic Health Record Data in Comparative Effectiveness Research

Caveats for the Use of Operational Electronic Health Record Data in Comparative Effectiveness Research
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DOI:
10.1097/mlr.0b013e31829b1dbd
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发表时间:
2013-08-01
期刊:
影响因子:
3
通讯作者:
Saltz, Joel H.
Saltz, Joel H.
中科院分区:
医学3区
文献类型:
--
作者:
Hersh, William R.;Weiner, Mark G.;Saltz, Joel H.

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业务电子健康记录系统中的数据量不断增长,为许多任务(包括比较有效性研究)的重复使用提供了前所未有的机会。然而,使用这些数据有许多注意事项。来自临床环境的电子健康记录数据可能不准确,不完整,以破坏其意义的方式转换,无法恢复用于研究,来源不明,粒度不足,并且与研究方案不兼容。然而,这些数据的数量和现实世界的性质为它们的使用提供了动力,我们开发了一个警告列表,以告知这些数据的潜在用户,并提供了一个信息学路线图,旨在确保能够最好地利用这一机会来增强比较有效性研究。
The growing amount of data in operational electronic health record systems provides unprecedented opportunity for its reuse for many tasks, including comparative effectiveness research. However, there are many caveats to the use of such data. Electronic health record data from clinical settings may be inaccurate, incomplete, transformed in ways that undermine their meaning, unrecoverable for research, of unknown provenance, of insufficient granularity, and incompatible with research protocols. However, the quantity and real-world nature of these data provide impetus for their use, and we develop a list of caveats to inform would-be users of such data as well as provide an informatics roadmap that aims to insure this opportunity to augment comparative effectiveness research can be best leveraged.