Epidemic and pandemic viral infections: impact on tuberculosis and the lung: A consensus by the World Association for Infectious Diseases and Immunological Disorders (WAidid), Global Tuberculosis Network (GTN), and members of the European Society of Clinical Microbiology and Infectious Diseases Study Group for Mycobacterial Infections (ESGMYC).
Epidemic and pandemic viral infections: impact on tuberculosis and the lung: A consensus by the World Association for Infectious Diseases and Immunological Disorders (WAidid), Global Tuberculosis Network (GTN), and members of the European Society of Clinical Microbiology and Infectious Diseases Study Group for Mycobacterial Infections (ESGMYC).
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DOI：
10.1183/13993003.01727-2020
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发表时间：
2020-10
期刊：
影响因子：
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通讯作者：
Goletti D
中科院分区：
文献类型：
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作者：
Ong CWM;Migliori GB;Raviglione M;MacGregor-Skinner G;Sotgiu G;Alffenaar JW;Tiberi S;Adlhoch C;Alonzi T;Archuleta S;Brusin S;Cambau E;Capobianchi MR;Castilletti C;Centis R;Cirillo DM;D'Ambrosio L;Delogu G;Esposito SMR;Figueroa J;Friedland JS;Ho BCH;Ippolito G;Jankovic M;Kim HY;Rosales Klintz S;Ködmön C;Lalle E;Leo YS;Leung CC;Märtson AG;Melazzini MG;Najafi Fard S;Penttinen P;Petrone L;Petruccioli E;Pontali E;Saderi L;Santin M;Spanevello A;van Crevel R;van der Werf MJ;Visca D;Viveiros M;Zellweger JP;Zumla A;Goletti D
重大流行病，包括一些符合大流行标准的流行病，如严重急性呼吸系统综合症、中东呼吸综合征、艾滋病毒、甲型H1N1流感和最近的新冠肺炎，都会影响肺部。结核病(TB)仍然是头号传染病杀手，但除了合并型结核病/艾滋病毒外，人们对病毒流行和大流行与结核病的相互作用知之甚少。这份基于共识的文件的目的是描述导致流行病和影响肺部的大流行(MERS、SARS、艾滋病毒、甲型H1N1流感)的病毒感染的影响及其与结核病的相互作用。对科学文献进行了搜索。成立了一个由国际专家组成的撰写委员会，其中包括欧洲疾病预防和控制公共卫生应急中心(ECDC PHE)小组、世界传染病和免疫紊乱协会(WAIDID)、全球结核病网络(GTN)和欧洲临床微生物学和传染病学会(ESCMID)分枝杆菌感染研究小组的成员。在编写委员会和一个更大的专家组之间进行了多轮修订后，达成了共识。涉及核心作者组(不包括ECDC PHE团队)的德尔福过程确定了需要审查/协商一致的领域，随后进行了第二轮，以细化最终共识要素。讨论了这些病毒感染的流行病学和免疫学及其与结核病的相互作用，以及对空气传播感染的诊断、治疗和预防(感染控制、病毒控制和工作场所安全)的影响。这份协商一致文件对这一专题的已知情况进行了迅速和全面的总结。这份共识声明描述了导致流行病和影响肺部的大流行的病毒感染的影响(中东呼吸综合征、非典、艾滋病毒、甲型H1N1流感pdm/09和新冠肺炎)及其与结核病的相互作用，结核病是头号传染病杀手https://bit.ly/2UUjhGu。
Major epidemics, including some that qualify as pandemics, such as severe acute respiratory syndrome (SARS), Middle East respiratory syndrome (MERS), HIV, influenza A (H1N1)pdm/09 and most recently COVID-19, affect the lung. Tuberculosis (TB) remains the top infectious disease killer, but apart from syndemic TB/HIV little is known regarding the interaction of viral epidemics and pandemics with TB. The aim of this consensus-based document is to describe the effects of viral infections resulting in epidemics and pandemics that affect the lung (MERS, SARS, HIV, influenza A (H1N1)pdm/09 and COVID-19) and their interactions with TB. A search of the scientific literature was performed. A writing committee of international experts including the European Centre for Disease Prevention and Control Public Health Emergency (ECDC PHE) team, the World Association for Infectious Diseases and Immunological Disorders (WAidid), the Global Tuberculosis Network (GTN), and members of the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) Study Group for Mycobacterial Infections (ESGMYC) was established. Consensus was achieved after multiple rounds of revisions between the writing committee and a larger expert group. A Delphi process involving the core group of authors (excluding the ECDC PHE team) identified the areas requiring review/consensus, followed by a second round to refine the definitive consensus elements. The epidemiology and immunology of these viral infections and their interactions with TB are discussed with implications for diagnosis, treatment and prevention of airborne infections (infection control, viral containment and workplace safety). This consensus document represents a rapid and comprehensive summary on what is known on the topic. This consensus statement describes the effects of the viral infections resulting in epidemics and pandemics affecting the lung (MERS, SARS, HIV, influenza A (H1N1)pdm/09 and COVID-19) and their interactions with TB, the top infectious disease killer https://bit.ly/2UUjhGu