Establishment of a serum IgG4 cut-off value for the differential diagnosis of IgG4-related disease in Chinese population

Establishment of a serum IgG4 cut-off value for the differential diagnosis of IgG4-related disease in Chinese population
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DOI:
10.3109/14397595.2015.1117171
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发表时间:
2016-01-01
影响因子:
2.2
通讯作者:
Li, Yongzhe
Li, Yongzhe
中科院分区:
医学3区
文献类型:
--
作者:
Li, Ping;Chen, Hua;Li, Yongzhe

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目的:本研究旨在更好地了解与血清IgG4浓度相关的诊断,并探讨在中国人群中开发血清IgG4检测IgG4相关疾病(IgG4- rd)的可能性。方法:回顾性分析北京协和医院4年间497例血清IgG4亚类测定结果,其中IgG4- rd 242例,其他疾病130例,健康人群125例。结果:IgG4- rd组血清IgG4浓度显著高于其他病理组(1662.93760.9mg/L, p
Objective: This study was performed to better know diagnosis associated with serum IgG4 concentration, and to explore the possibility for development of a serum IgG4 for IgG4-related disease (IgG4-RD) in Chinese populations.Methods: We studied retrospectively 497 IgG4 serum subclass measurements from Peking Union Medical College Hospital during the four-year period, including 242 IgG4-RD, 130 other diseases and 125 healthy individuals.Results: Serum IgG4 concentrations were significantly higher in IgG4-RD than in other pathologies (1662.93760.9mg/L, p