Brown adipose tissue: the dominant site of nonshivering thermogenesis in the rat.

Brown adipose tissue: the dominant site of nonshivering thermogenesis in the rat.
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棕色脂肪组织:大鼠非颤抖产热的主要部位。

DOI:
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发表时间:
1978
期刊:
Experientia. Supplementum
影响因子:
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通讯作者:
M. Lorraine Frydman
M. Lorraine Frydman
中科院分区:
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文献类型:
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作者:
David O. Foster;M. Lorraine Frydman

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用示踪微球测量与去甲肾上腺素(NA)诱导的热习服和冷习服(CA)大鼠的组织血流量变化相关的组织血流量变化,发现流向棕色脂肪组织(BAT)的血流量显著增加。血流量数据和跨肩峰动脉血氧分压差的测量表明,在NA诱导的CA大鼠非颤抖产热(NST)中,BAT至少占60%。骨骼肌被发现在这种NST中只有很少的参与,如果有的话。
Measurements with tracer microspheres of changes in tissue blood flow associated with noradrenaline (NA)-induced calorigenesis in warm-acclimated and in cold-acclimated (CA) rats revealed very large increases in flow to brown adipose tissue (BAT). The data on flow together with measurements of the arteriovenous difference in blood O2 across interscapular BAT indicate that BAT accounts for at least 60% of the NA-induced nonshivering thermogenesis (NST) of CA rats. Skeletal muscle was found to be only minimally, if at all, involved in this NST.