Universal Screening vs. Risk-based Strategy for Prevention of Early-onset Neonatal Group-B Streptococcal Disease
Universal Screening vs. Risk-based Strategy for Prevention of Early-onset Neonatal Group-B Streptococcal Disease
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DOI：
10.1093/tropej/fmr014
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发表时间：
2011-12-01
影响因子：
2
通讯作者：
Mohammed, Abdelbaset Fakhry
中科院分区：
文献类型：
--
作者：
Abdelmaaboud, Mohamed;Mohammed, Abdelbaset Fakhry
目的：评估普遍筛查和基于风险的策略在预防早发 B 族链球菌 (EOGBS) 疾病方面的差异。受试者：通过检索微生物实验室的计算机数据库，确定了 2003 年至 2009 年的 EOGBS 疾病病例。干预措施：通过在妊娠 35-37 周时采集直肠阴道拭子和尿培养，对所有孕妇以及就诊时的所有高危病例进行 B 族链球菌孕产妇筛查。结果：2003年至2009年，共记录活产87 260例，其中极低出生体重儿1 948例。我们审查了从活产总数中随机抽取的 1268 名活产的分娩记录。研究期间发现了 45 例 EOGBS 疾病（总体发病率为每 1000 名活产儿 0.51 例）。
Objective: To evaluate the difference between universal screening and risk-based strategies in the prevention of early-onset Group-B streptococcal (EOGBS) disease. Subjects: Cases of EOGBS disease from 2003 to 2009 were identified by a search of the microbiology laboratory's computerized database. Interventions: Maternal screening for Group-B Streptococci was done for all pregnant women by taking rectovaginal swabs and urine culture at 35-37 weeks of gestation and for all high-risk cases at the time of presentation. Results: From 2003 to 2009, a total of 87 260 live births were recorded, 1948 neonates were very low-birth weight. We reviewed labor and delivery records for 1268 live births randomly sampled from total live births. Forty-five cases of EOGBS disease were identified during the period of study (overall incidence of 0.51 cases per 1000 live births).