Mercury concentration in organs of contemporary Japanese.
Mercury concentration in organs of contemporary Japanese.
复制标题
当代日本人器官中的汞浓度。
DOI：
10.1080/00039896.1989.9935897
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发表时间：
1989
期刊：
影响因子：
--
通讯作者：
H. Akagi
中科院分区：
文献类型：
--
作者：
N. Matsuo;T. Suzuki;H. Akagi
对46名日本受试者的尸检样本进行了无机汞(IHG)、甲基汞(MeHg)和总汞(THG)浓度的测定。两个实验室(实验室A和B)参与了汞分析：实验室A用于三汞和三氢汞，实验室B用于三汞和甲基汞。两个实验室的总汞浓度值一致：肾皮质、肾髓质和肝脏的平均值为数百ng/g，大脑、小脑、心脏和脾的平均值为数十ng/g。无机汞在肾脏和肝脏中的积累量较大，肾脏、肝脏、心脏、脾、大脑和小脑中无机汞的积累量分别为81-84%、67%、25%、22%、20%和14%。除肝脏外，组织中的甲基汞含量在所有器官中都是一致的。在大脑、小脑、心脏和脾中约有80%以甲基汞的形式存在，而在肝脏、肾髓质和肾皮质中分别为33%、15%和11%。年龄是导致大脑和心脏中IHG浓度升高、大脑、小脑和心脏中%MeHg值降低、大脑和心脏中%IHG值升高的显著因素。
Concentrations of inorganic mercury (IHg), methylmercury (MeHg), and total mercury (THg) were determined for autopsy samples from 46 Japanese subjects. Two laboratories (Labs A and B) participated in Hg analyses: Lab A for THg and IHg and Lab B for THg and MeHg. Total mercury concentration values were in good agreement between the two laboratories: the averages were several hundreds of ng/g in kidney cortex, kidney medulla, and liver, and were several tens of ng/g in cerebrum, cerebellum, heart, and spleen. Inorganic mercury accumulated more in kidney and liver: its percentage THg was 81-84% in the kidney, 67% in the liver, 25% in the heart, 22% in the spleen, 20% in the cerebrum, and 14% in the cerebellum. Methylmercury levels in tissues were uniform through all organs except the liver. Approximately 80% was in the form of MeHg in the cerebrum, cerebellum, heart, and spleen, whereas the values were 33%, 15%, and 11% in the liver, kidney medulla, and kidney cortex, respectively. Age was a significant factor in increased IHg concentrations in the cerebrum and heart, decreased values of %MeHg in the cerebrum, cerebellum, and heart, and increased values of %IHg in the cerebrum and heart.