SWINE INFLUENZA-VIRUS INFECTIONS IN HUMANS
SWINE INFLUENZA-VIRUS INFECTIONS IN HUMANS
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DOI：
10.1093/infdis/136.supplement_3.s386
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发表时间：
1977-01-01
影响因子：
6.4
通讯作者：
HATTWICK, MAW
中科院分区：
文献类型：
--
作者：
DOWDLE, WR;HATTWICK, MAW
1918年，猪流感首次被认为是一种流行性疾病。同年，人类流感病毒引发了有记录以来最严重的大流行。猪流感病毒于1930年被分离出来。猪流感病毒于1974年首次从人身上分离出来。自那以后，包括迪克斯堡的病例在内，美国总共有九例从人类身上分离出病毒。还获得了人类感染猪流感病毒的血清学证据。1974年以前将猪流感病毒传播给人类的证据很少，而且是间接的。最近对猪流感病毒感染的认识可能是由于更好的监测、更多的易感人群或增加了对人类的病毒传染性。然而，人类感染的明显频率和人类群体中猪流感病毒抗体水平的下降表明，猪流感病毒可能是人类流行病的潜在来源。
Influenza in swine was first recognized as an epizootic disease in 1918. During that same year influenza virus in humans caused the worst pandemic on record. The virus of swine influenza was isolated in 1930. Swine influenza virus was first isolated from humans in 1974. Since then, including the cases at Fort Dix, there have been a total of nine viral isolations from humans in the United States. Serologic evidence of infections with swine influenza virus in humans has also been obtained. Evidence for transmission of swine influenza virus to humans before 1974 is minimal and circumstantial. Recent recognition of infections with swine influenza virus may be the result of better surveillance, increased numbers of susceptible humans, or increased viral infectivity for humans. Nevertheless, the apparent frequency of human infections and the declining levels of antibodies to swine influenza virus in the human population suggest that influenza viruses of swine may be a potential source of epidemic disease for humans.