Standardization of insulin immunoassays: Report of the American Diabetes Association Workgroup
Standardization of insulin immunoassays: Report of the American Diabetes Association Workgroup
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DOI:
10.1373/clinchem.2006.082214
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发表时间:
2007-04-01
影响因子:
9.3
通讯作者:
Steffes, Michael W.
中科院分区:
文献类型:
--
作者:
Marcovina, Santica;Bowsher, Ronald R.;Steffes, Michael W.
Background: Circulating insulin concentration in serum or plasma provides important information for the estimation of insulin secretion and insulin resistance. Currently, lack of standardization of insulin assays hinders efforts to achieve consistent measures for treatment guidelines.Methods: A Workgroup convened by the American Diabetes Association evaluated 12 different commercial insulin methods from 9 manufacturers.Results: The within-assay CVs ranged from 3.7% to 39.0%, with 7 of 10 assays having a CV