Histopathologic changes after pericardial patch tracheoplasty.
Histopathologic changes after pericardial patch tracheoplasty.
复制标题
心包补片气管成形术后的组织病理学变化。
DOI：
10.1001/archotol.1997.01900100043006
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发表时间：
1997
期刊：
影响因子：
--
通讯作者：
F. Gonzalez
中科院分区：
文献类型：
--
作者：
A. Cheng;C. Backer;L. Holinger;M. Dunham;C. Mavroudis;F. Gonzalez
应用心包补片气管成形术治疗婴幼儿完全性气管环所致的长段先天性气管狭窄。2例婴儿的病史，描述了他们各自气管的组织病理学变化。移植物部位的纤毛假复层柱状上皮完全再上皮化，提示气管内有正常的粘液纤毛流动。移植部位的心包补片被成熟的疤痕组织取代，建立了一个功能良好的气管腔。对气管的伤口愈合进行了综述。肉芽组织旺盛造成的梗阻是一个持续的问题。对于患有长段先天性气管狭窄的婴儿，心包仍是一种重要的移植材料。
Pericardial patch tracheoplasty has been used for surgical correction of long-segment congenital tracheal stenosis caused by complete tracheal rings in infants. The case histories of 2 infants with descriptions of the histopathologic changes in their respective tracheas are presented. Complete reepithelialization of the graft site with ciliated pseudostratified columnar epithelium was found, suggesting the likelihood of normal mucociliary flow in the trachea. The pericardial patches were replaced by mature scar tissue in the graft site, establishing a functional tracheal lumen. Wound healing in the trachea is reviewed. Obstruction by exuberant granulation tissue is an ongoing concern. Pericardium continues to be an important option as graft material for tracheal reconstruction in infants with long-segment congenital tracheal stenosis.