Ciprofloxacin-induced anaphylactoid reaction
Ciprofloxacin-induced anaphylactoid reaction
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DOI：
10.1007/s00431-006-0099-y
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发表时间：
2006-08-01
影响因子：
3.6
通讯作者：
Dayal, Devi
中科院分区：
文献类型：
--
作者：
Kothur, Kavitha;Singh, Meenu;Dayal, Devi
氟喹诺酮类药物是萘啶酸的合成衍生物，广泛用于细菌感染的治疗。它们通常是安全且耐受性良好的。最常见的不良反应包括胃肠道不适、头痛、头晕、转氨炎、光敏、心动过速、QTc延长和皮疹。氟喹诺酮类药物也有类过敏反应的报道，最明显的是环丙沙星，发生率为0.46 - 1.2/10万接受治疗的患者[1,4]。
DiscussionFluoroquinolones, synthetic derivatives of nalidixic acid, are widely used in the management of bacterial infections. They are known to be generally safe and well tolerated. The most common adverse reactions include gastrointestinal complaints, headache, dizziness, transaminitis, photosensitivity, tachycardia, QTc prolongation and rash. Anaphylactoid reactions also have been reported with fluoroquinolones, most notably with ciprofloxacin, with a incidence of 0.46–1.2/100,000 patients treated [1, 4].