Introduction to the special issue on: A new view of hippocampal area CA2.
Introduction to the special issue on: A new view of hippocampal area CA2.
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特刊介绍：海马区CA2的新观点。
DOI：
10.1002/hipo.23514
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发表时间：
2023
期刊：
影响因子：
3.5
通讯作者：
Farris,Shannon
中科院分区：
文献类型：
--
作者：
Dudek,SerenaM;Alexander,GeorgiaM;Farris,Shannon
两张图都是老鼠的组织。gl迄今为止，还没有分子标记物能够清楚地区分接受苔藓纤维的CA 2神经元和Lorente de Nó的CA 2神经元，然而苔藓纤维的存在或缺失表明存在两个不同的CA 2神经元群体。评论中提出的关键问题是艾伦研究所的小鼠脑图谱没有列出腹侧海马体中的CA 2的可能原因（Lein等人，[33])以及是否存在CA 2内细胞异质性的证据。区域CA 2的定义，甚至它的存在，也许是这种混乱状态的最好例子（更不用说如果CA 2没有被正确定义，那么CA 1和CA 3都不能被正确定义）。(b)Lorente de Nó创造了CA 1、CA 2和CA 3区域，根据定义，CA 2神经元不接受来自齿状颗粒细胞的输入（苔藓纤维的末端用青色箭头标记）。[摘自文章]海马的版权是Wiley-Blackwell的财产，未经版权保持器的明确书面许可，其内容不得复制或通过电子邮件发送到多个网站或发布到列表服务器。但是，用户可以打印，下载或电子邮件的文章供个人使用。这篇摘要可以删节。不保证副本的准确性。用户应参考原始出版版本的材料的完整摘要。版权适用于所有摘要。
Both drawings are of tissue from mice. gl As yet, no molecular marker has been identified that clearly distinguishes between the CA2 neurons receiving mossy fibers, and those in Lorente de Nó's CA2 that do not, yet the absence or presence of mossy fibers suggests that there are two distinct populations of CA2 neurons. Key issues addressed in the commentary are possible reasons why the Allen Institute's mouse brain atlas does not list a CA2 in the ventral hippocampus (Lein et al.,[33]), and whether there is evidence of cellular heterogeneity within the CA2. The definition of area CA2, and even its existence, is perhaps the best example of such a confused state (not to mention that neither CA1 nor CA3 can be properly defined if CA2 is not).(b) Lorente de Nó coined the CA1, CA2, and CA3 areas, with CA2 neurons, by definition, not receiving input from the dentate granule cells (end of the mossy fibers marked with a cyan arrow).[Extracted from the article]Copyright of Hippocampus is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. Copyright applies to all Abstracts.