Translation control: Connecting mitogens and the ribosome

Translation control: Connecting mitogens and the ribosome
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DOI:
10.1016/s0960-9822(98)70152-6
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发表时间:
1998-03-26
期刊:
影响因子:
9.2
通讯作者:
Schreiber, SL
Schreiber, SL
中科院分区:
生物学1区
文献类型:
--
作者:
Peterson, RT;Schreiber, SL

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3-磷酸​​肌醇依赖性激酶 1 (PDK1) 被鉴定为难以捉摸的 70 kDa S6 激酶激酶之一,填补了细胞外受体调节翻译的信号传导途径的空白。它会导致我们重新考虑先前确定的途径成员之间的关系吗?
The identification of 3-phosphoinositide-dependent kinase 1 (PDK1) as one of the elusive 70 kDa S6 kinase kinases has filled a gap in the signaling pathway by which extracellular receptors regulate translation. Will it cause us to reconsider the relationships between previously identified members of the pathway?