EFFECTS OF PENTOBARBITAL AND PROGESTERONE ON RANDOM RATIO RESPONDING IN MALE AND FEMALE RATS
EFFECTS OF PENTOBARBITAL AND PROGESTERONE ON RANDOM RATIO RESPONDING IN MALE AND FEMALE RATS
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DOI：
10.1007/bf00179930
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发表时间：
1987-01-01
影响因子：
3.4
通讯作者：
VANDEPOLL, NE
中科院分区：
文献类型：
--
作者：
HEINSBROEK, RPW;VANHAAREN, F;VANDEPOLL, NE
完整的雄性和卵巢切除的雌性大鼠进行训练，以杠杆按下的随机比例（RR）计划的食物强化。本文研究了不同剂量戊巴比妥（1-16 mg/kg）和孕酮（10-80 mg/kg）对反应输出的影响。低剂量戊巴比妥增加反应，高剂量降低反应。在高剂量戊巴比妥的心率降低效应中观察到性别差异。预后增加卵巢切除女性的反应率，但不影响在完整的男性。
Intact male and ovariectomized female rats were trained to lever press under a random ratio (RR) schedule of food reinforcement. Effects of different doses of pentobarbital (1-16 mg/kg) and progesterone (10-80 mg/kg) on response output were studied. Low doses of pentobarbital increased responding, high doses decreased responding. Sex differences were observed in the rate-decreasing effects of high doses of pentobarbital. Progesterone increased the response rate of ovariectomized females, but did not affect responding in intact males.