Overall cost in the treatment of otitis media
Overall cost in the treatment of otitis media
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DOI：
10.1097/00006454-199702001-00003
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发表时间：
1997-02-01
影响因子：
3.6
通讯作者：
Cunningham, JR
中科院分区：
文献类型：
--
作者：
Kaplan, B;Wandstrat, TL;Cunningham, JR
背景。有多种抗菌药物可用于治疗中耳炎 (OM)；然而，人们对这些药物的相对成本效益知之甚少。方法。我们开发了一种非侵入性观察模型来评估 OM 治疗中常用抗生素的总成本（直接和间接）。我们还收集了复发率的数据，这会显着影响成本。结果。本研究中治疗 OM 发作的平均总费用为 115.80 美元。复发性 OM 发作的治疗费用明显高于初次发作的治疗费用（124.64 美元 vs. 107.81 美元，P = 0.0001）。这项研究表明，巨额成本与 OM 治疗相关，而抗生素价格仅占该成本的一小部分。复发率似乎因不同抗生素治疗而异。结论。我们的结论是，复发是 OM 治疗费用的主要决定因素。与较低复发率相关的药物通常是最具成本效益的治疗选择。
Background. Numerous antimicrobial agents are available for treatment of otitis media (OM); however, little is known about the relative cost effectiveness of these drugs.Methods. We developed a noninvasive, observational model to assess the total costs (direct and indirect) associated with commonly used antibiotics in the therapy of OM. We also gathered data on recurrence rates, which can significantly affect costs.Results. The average total cost of treating an episode of OM in this study was $115.80. Treatment of a recurrent OM episode was significantly more costly than treatment of an initial episode ($124.64 vs. $107.81, P = 0.0001). This study suggests that significant costs are associated with OM treatment and that antibiotic price constitutes only a small portion of this cost. Recurrence rates appeared to vary with various antibiotic treatments.Conclusion. We conclude that recurrence is a major determinant of OM treatment costs. Drugs associated with lower rates of recurrence will usually be the most cost-effective treatment options.