The influence of vasopressin on the regional uptake of [3H] orotic acid by rat brain.
The influence of vasopressin on the regional uptake of [3H] orotic acid by rat brain.
复制标题
加压素对大鼠脑局部摄取[3H]乳清酸的影响。
DOI：
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发表时间：
1978
期刊：
影响因子：
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通讯作者：
A. Ermisch
中科院分区：
文献类型：
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作者：
R. Landgraf;J. Hess;A. Ermisch
在大鼠颈动脉内注射后，15秒后断头，测量18个脑区和垂体前叶对RNA前体[3 H]乳清酸的摄取。同时注射赖氨酸-8-加压素（1，10，100，1000和10000 μ U每毫升注射液，分别）引起的剂量依赖性增强示踪剂的摄取7个区域，例如海马。有迹象表明，特别是在这个区域的血脑屏障渗透性的前体肽激素的影响。
After intracarotid injection in the rat followed by decapitation 15 s later, the uptake of the RNA precursor [3H] orotic acid by 18 brain region and by the anterior pituitary was measured. Simultaneously injected lysine-8-vasopressin (1, 10, 100, 1000 and 10000 muU per ml injection solution, respectively) caused a dose-dependent enhancement of tracer uptake by 7 regions, e.g. by the hippocampus. There are indications that especially in this region the blood-brain barrier permeability to the precursor was influenced by the peptide hormone.