Current concepts in peritoneal dialysis.
Current concepts in peritoneal dialysis.
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腹膜透析的当前概念。
作者：
A. Kliger
腹膜透析越来越多地用于治疗终末期肾衰竭患者。通过使用高渗透析液增加超滤，注入腹腔内血管扩张剂以增加有效的交换表面积，以及采用新的透析液输送方法来改善透析液混合和降低膜对溶质通量的有效阻力，可以增强溶质运输。虽然感染仍然是腹膜透析的主要并发症，但预防和治疗感染的技术已得到有效应用。腹膜透析治疗糖尿病患者也取得了进展。连续非卧床腹膜透析是一项临床应用迅速发展的新技术，可能是许多终末期肾衰竭患者的治疗选择。
Peritoneal dialysis has been increasingly employed to treat patients with end-stage renal failure. Solute transport can be enhanced by increasing ultrafiltration with hypertonic dialysate, infusing intraperitoneal vasodilators to increase the effective surface area for exchange, and by employing new methods of dialysate delivery which may improve dialysate mixing and decrease the effective membrane resistance to solute flux. While infection remains a major complication of peritoneal dialysis, techniques to prevent and treat infections have been effectively employed. Progress has also been made in the treatment of diabetic patients with peritoneal dialysis. Continuous ambulatory peritoneal dialysis, a relatively new technique with fast growing clinical application, may be the therapy of choice for many patients with end-stage renal failure.