Evaluation of shear wave dispersion in hepatic viscoelastic models including fibrous structure
Evaluation of shear wave dispersion in hepatic viscoelastic models including fibrous structure
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DOI：
10.7567/1347-4065/ab1a2c
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发表时间：
2019-07-01
影响因子：
1.5
通讯作者：
Shiina, Tsuyoshi
中科院分区：
文献类型：
--
作者：
Fujii, Shiori;Yamakawa, Makoto;Shiina, Tsuyoshi
在慢性肝炎的诊断中，剪切波弹性成像用于通过从剪切波速度估计粘弹性来评估纤维化进展。研究了离散斜率法评价粘度和纤维化程度。然而，当剪切波长略大于肝纤维化组织中纤维结构的尺寸时，剪切波重复反射或折射传播，并影响色散斜率。我们模拟了剪切波在一个模型中的传播与纤维结构和比较的色散斜率与均匀模型，以调查纤维结构的效果。结果，分散斜率在高频范围内取决于粘度，但在低频范围内受纤维结构的影响。结果表明，纤维结构影响低频成分。利用不同的频率范围来估计频散斜率可以帮助更精确的粘弹性分析。(C)2019日本应用物理学会
In diagnosis of chronic hepatitis, shear wave elastography is utilized for the evaluation of fibrosis progression by estimating the viscoelasticity from shear wave speeds. The dispersion slope method is studied to evaluate the viscosity and fibrosis stage. However, when the shear wave length is a little larger than the size of fibrous structure in liver fibrosis tissues, shear wave propagates repeating reflection or refraction and influences the dispersion slope. We simulate shear wave propagation in a model with a fibrous structure and compare the dispersion slope with a homogeneous model in order to investigate the effect of the fibrous structure. As a result, the dispersion slope is dependent on the viscosity in a high frequency range but affected by the fibrous structure in a low frequency range. Results show that the fibrous structure influences contents of low frequencies. Using different frequency ranges to estimate the dispersion slope can help more precise viscoelasticity analysis. (C) 2019 The Japan Society of Applied Physics