Bonding BisGMA to dentin - a proof of concept for hydrophobic dentin bonding
Bonding BisGMA to dentin - a proof of concept for hydrophobic dentin bonding
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DOI：
10.1177/154405910708601103
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发表时间：
2007-11-01
影响因子：
7.6
通讯作者：
Tay, K. C. Y.
中科院分区：
文献类型：
--
作者：
Tay, F. R.;Pashley, D. H.;Tay, K. C. Y.
在用于乙醇湿粘合的疏水粘合剂的配制中使用TEGDMA作为稀释剂共聚单体是一个问题，这是由于其浸出潜力、较高的吸水性和生物不相容性。本研究测试了仅使用乙醇溶剂化的BisGMA可以实现与酸蚀牙本质的疏水键合的假设。在20 cm水压下，使用乙醇湿粘结的实验性BisGMA粘合剂，磷酸蚀刻、磷酸盐封闭、深冠牙本质的抗拉强度与根据Aluminer-recommended方案使用OptiBond FL粘合的抗拉强度无显著差异，具有相似的耐酸/耐碱混合层、树脂标签和纳米渗漏分布。乙醇替代水饱和的牙本质产生更宽的纤维间空间，更广泛的胶原纤维的收缩，和更窄的混合层。实验性BisGMA粘合剂提供了概念证明，即相对疏水的树脂可以通过经由乙醇替代增加其疏水特性而偶联到酸蚀刻的牙本质。在临床应用前应进一步优化。
The use of TEGDMA as a diluent comonomer in the formulation of hydrophobic adhesives for ethanol wet-bonding is a concern, due to its leaching potential, higher water sorption, and bio-incompatibility. This study tested the hypothesis that hydrophobic bonding to acid-etched dentin may be accomplished with the use of ethanol-solvated BisGMA only. Phosphoric-acid-etched, oxalate-occluded, deep coronal dentin bonded under 20 cm water pressure with experimental BisGMA adhesives by ethanol wet-bonding exhibited tensile strengths that were not significantly different from that achieved with OptiBond FL bonded according to the manufacturer-recommended protocol, with similar acid-/base-resistant hybrid layers, resin tags, and nanoleakage distribution. Ethanol replacement of water-saturated dentin produced wider interfibrillar spaces, more extensive shrinkage of the collagen fibrils, and narrower hybrid layers. Experimental BisGMA adhesives provide the proof of concept that relatively hydrophobic resins may be coupled to acid- etched dentin by increasing its hydrophobic characteristics via ethanol replacement. They should be further optimized before clinical application.