Carbohydrate Self-Assembly at Surfaces: STM Imaging of Sucrose Conformation and Ordering on Cu(100)
Carbohydrate Self-Assembly at Surfaces: STM Imaging of Sucrose Conformation and Ordering on Cu(100)
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DOI：
10.1002/anie.201901340
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发表时间：
2019-06-17
影响因子：
16.6
通讯作者：
Kern, Klaus
中科院分区：
文献类型：
--
作者：
Abb, Sabine;Tarrat, Nathalie;Kern, Klaus
糖是一种普遍存在的生物分子，但人们对它们与表面的相互作用和组装知之甚少。通过将制备质谱法与扫描隧道显微镜相结合，我们已经能够用亚单位水平成像来解决铜（100）表面上双糖蔗糖的构象和自组装。通过采用多阶段建模方法结合实验数据，我们可以合理化表面上的构象以及蔗糖分子之间的相互作用，从而得到在表面上观察到的自组装图案的模型。
Saccharides are ubiquitous biomolecules, but little is known about their interaction with, and assembly at, surfaces. By combining preparative mass spectrometry with scanning tunneling microscopy, we have been able to address the conformation and self-assembly of the disaccharide sucrose on a Cu(100) surface with subunit-level imaging. By employing a multistage modeling approach in combination with the experimental data, we can rationalize the conformation on the surface as well as the interactions between the sucrose molecules, thereby yielding models of the observed self-assembled patterns on the surface.