The occurrence of vaginal infections among HIV-infected and high-risk HIV-uninfected women - Longitudinal findings of the women"s interagency HIV study
The occurrence of vaginal infections among HIV-infected and high-risk HIV-uninfected women - Longitudinal findings of the women"s interagency HIV study
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DOI：
10.1097/01.qai.0000242448.90026.13
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发表时间：
2006-10-01
影响因子：
3.6
通讯作者：
Greenblatt, Ruth M.
中科院分区：
文献类型：
--
作者：
Watts, D. Heather;Springer, Gayle;Greenblatt, Ruth M.
Objectives: To evaluate changes over time in rates of bacterial vaginosis (BV), trichomoniasis (TV), and yeast vaginitis (YV) among HIV-infected and similar HIV-uninfected women.Methods: Two thousand fifty-six HIV-infected women and 554 HIV-uninfected women were evaluated semiannually from 1994 until March 2003 in a prospective cohort study. BV was diagnosed by Gram stain, TV by wet mount, and YV by symptoms with microscopically visible hyphae or positive culture. Trends were assessed using Poisson models.Results: At baseline, BV was present in 42.8% and 47.0% of HIV-infected and uninfected women (P = 0.21), TV in 6.1% and 7.8% (P = 0.17), and YV in 10.0% and 3.8% (P < 0.001). Over time, rates of BV and TV decreased significantly in both groups, whereas rates of YV declined only among HIV-infected women. Risk of BV was not associated with HIV status, whereas HIN-infected women had a lower risk of TV Highly active antiretroviral therapy (HAART) use was associated with decreased risk of all 3 infections.Conclusions: Declines in BV, TV, and YV represent decreased morbidity for HIV-infected women and, potentially, decreased risk of transmission of HIV because each has been associated with increased genital detection of HIV.
