Screen-detected mucinous breast carcinoma: Potential for delayed diagnosis
Screen-detected mucinous breast carcinoma: Potential for delayed diagnosis
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DOI：
10.1016/j.crad.2005.10.008
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发表时间：
2006-05-01
影响因子：
2.6
通讯作者：
Wylie, E
中科院分区：
文献类型：
--
作者：
Dhillon, R;Depree, P;Wylie, E
目的：描述34个屏幕检测粘液癌insure.MATERIALS和METHODS的影像学特征：乳腺癌筛查西澳大利亚州（WA）数据库之间的1991年1月和2003年12月进行了检索。在此期间，对214 507名妇女进行了筛查，记录了2 745例浸润性癌和45例粘液癌。本文回顾性分析黏液癌的病例、影像学及病理报告。34个radiotogicatly检测纯粘液性carcinomas described.Results：纯粘液性carcinomas，诊断的平均年龄为65岁（范围48-82岁），这是高于其他女性乳腺癌（平均年龄60岁）筛选在乳腺癌筛查WA。黏液癌的特征性X线表现为边界清楚、边缘分叶状的肿块（26/34）。超声仅检出39%（11/28）的肿瘤，因为直径小于15 mm的较小病变通常与正常脂肪呈等回声。在切除时报告组织学分级的情况下，大多数（25/26）为2至中等级别肿瘤（Bloom、Richardson和Elston I级和II级）。大量病变（13/34）在之前的筛选检查中很明显，被误解为良性病变。然而，这些情况下，没有一个积极的腋窝淋巴结在最终diagnosis.CONCLUSION：虽然乳腺摄影良性外观粘液癌造成延误诊断，目前的情况下，38%，粘液性乳腺癌有一个良好的预后，因为它们往往是二级肿瘤，很少转移。在筛查计划中延迟诊断这些肿瘤可能不会导致大多数妇女的显著不良后果。(c)2005年皇家放射科医师学院。出版社：Elsevier Ltd. rights reserved.
AIM: To describe the imaging features of 34 screen-detected mucinous carcinomas lesions.MATERIALS AND METHODS: The BreastScreen Western Australia (WA) database between January 1991 and December 2003 was searched. During this period, 214,507 women were screened and 2745 cases of invasive carcinoma and 45 cases of mucinous carcinoma were recorded. Case notes, radiology films and pathology reports of patients with mucinous carcinoma were reviewed. Thirty-four radiotogicatly detected pure mucinous carcinomas are described.RESULTS: Of the pure mucinous carcinomas, the average age at diagnosis was 65 years (range 48-82 years), which was higher than that of other women with breast cancer (average age 60 years) screened at BreastScreen WA. Characteristic mammographic features of mucinous carcinoma are well-circumscribed masses with lobulated margins (26/34). Only 39% (11/28) of tumours were detected at ultrasound, as the smatter Lesions less than 15 mm in diameter were often isoechoic with normal fat. Where histological grade was reported at excision, most (25/26) were tow to medium-grade tumours (Bloom, Richardson and Elston grade I and II). A significant number of lesions (13/34) were evident on the previous screening examination where they were misinterpreted as benign lesions. However, none of these cases had positive axitlary lymph nodes at final diagnosis.CONCLUSION: Although mammographically benign appearances of mucinous carcinoma caused a delay in diagnosis in 38% of the present cases, mucinous breast carcinomas have a favourable prognosis, as they are often tow-grade tumours and rarely metastasize. Delay in diagnosis for these tumours in a screening programme may not lead to a significant adverse outcome for most women. (c) 2005 The Royal College of Radiologists. Published by Elsevier Ltd. All. rights reserved.