The isolated and combined effects of selected physical activity and ibuprofen on delayed-onset muscle soreness
The isolated and combined effects of selected physical activity and ibuprofen on delayed-onset muscle soreness
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选定的身体活动和布洛芬对迟发性肌肉酸痛的单独和综合影响
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发表时间：
2005
期刊：
影响因子：
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通讯作者：
K. Ebrahim
中科院分区：
文献类型：
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作者：
N. Rahnama;F. Rahmani;K. Ebrahim
迟发性肌肉酸痛是指骨骼肌疼痛，经历了离心运动。本研究的目的是检查有或没有布洛芬的身体活动对延迟性肌肉酸痛的生理影响。44名非运动男性志愿者（年龄24.3 ± 2.4岁）被随机分配到四组之一：体力活动（n = 11），布洛芬（n = 11），体力活动和布洛芬（组合，n = 11），或对照组（n = 11）。 体力活动计划包括5分钟的步行和慢跑，10分钟的静态伸展的手和肩带，和5分钟的次最大收缩的同心运动。布洛芬消耗的单个个体的总量为2800毫克，这是采取从1小时之前的离心行动到48小时后，它。延迟发作的肌肉酸痛是通过执行70偏心收缩的肱二头肌肌肉的非优势侧上的一个修改的手臂卷曲机。在离心运动前1 h和离心运动后1、24和48 h，评估肌肉酸痛感、最大离心收缩、肌酸激酶活性和肘关节活动度。结果表明，在离心动作后，所有组的疼痛随时间增加（P<0.001），在24 h记录到最高值。 在24和48小时，对照组中观察到的疼痛大于体力活动组和联合组（P<0.001）。 离心运动后，肌酸激酶增加，与基线相比，所有组均升高（P<0.001），体力活动组和联合组的数值在48 h时恢复至基线。 然而，48 h后，对照组和布洛芬组的肌酸激酶仍显著高于基线水平。在24和48 h，对照组的肌酸激酶高于体力活动组和联合组（P<0.001）。 肘关节活动度也随时间减少（P <0.001）。 在1、24和48小时，对照组和布洛芬组的肘关节活动度的减少大于（P <0.001）体力活动组和联合组。 在24和48 h，对照组和布洛芬组的最大离心收缩的减少大于（P <0.001）体力活动组和联合组在48 h。 总之，这些结果增加了我们对体育活动以及体育活动和布洛芬联合使用对减轻离心运动引起的肌肉酸痛严重程度的影响的理解。在离心运动之前进行的身体活动会减轻肌肉酸痛。我们的研究结果表明，有或没有布洛芬的体力活动有助于防止延迟性肌肉酸痛。
Delayed-onset muscle soreness refers to the skeletal muscle pain that is experienced following eccentric exercise. The aim of the present study was to examine the physiological effects of physical activity with or without ibuprofen on delayed onset muscle soreness. Forty-four non-athletic male volunteers (age 24.3 ± 2.4 years) were randomly assigned to one of four groups: physical activity (n = 11), ibuprofen (n = 11), physical activity and ibuprofen (combination, n = 11), or control (n = 11). The physical activity programme comprised 5 min of walking and jogging, 10 min of static stretching of the hands and shoulder girdle, and 5 min of concentric movements with sub-maximal contractions. The total amount of ibuprofen consumed by a single individual was 2800 mg; this was taken from 1 h before the eccentric actions up to 48 h after it. Delayed onset muscle soreness was induced by performing 70 eccentric contractions of the biceps muscle of the non-dominant side on a modified arm curl machine. Perceived muscle soreness, maximal eccentric contraction, creatine kinase enzyme activity and elbow range of motion were assessed 1 h before and 1, 24 and 48 h after the eccentric actions. The results indicated that, after the eccentric actions, soreness increased (P < 0.001) across time in all groups, with the highest values being recorded at 24 h. At 24 and 48 h, greater soreness (P < 0.001) was observed in the control group than in the physical activity and combination groups. After the eccentric actions, creatine kinase increased and was elevated (P < 0.001) compared with baseline in all groups, with values returning to baseline in the physical activity and combination groups by 48 h. However, creatine kinase in the control and ibuprofen groups was still significantly higher than at baseline after 48 h. Creatine kinase was higher (P < 0.001) in the control group than in physical activity and combination groups at 24 and 48 h. There was also a reduction (P < 0.001) in elbow range of motion across time. This reduction in elbow range of motion was greater (P < 0.001) in the control and ibuprofen groups than in the physical activity and combination groups at 1, 24 and 48 h. The reduction in maximum eccentric contraction was greater (P < 0.001) in the control and ibuprofen groups than in the physical activity group at 24 and 48 h and the combination group at 48 h. In conclusion, the results add to our understanding of the effects of physical activity and the combination of physical activity and ibuprofen in reducing the severity of muscle soreness induced by eccentric exercise. Physical activity conducted before eccentric exercise alleviates muscle soreness. Our results indicate that physical activity with or without ibuprofen helps to prevent delayed-onset muscle soreness.