Basic mechanisms of the aging gastrointestinal tract
Basic mechanisms of the aging gastrointestinal tract
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DOI：
10.1159/000099474
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发表时间：
2007-01-01
影响因子：
2.3
通讯作者：
Salles, N.
中科院分区：
文献类型：
--
作者：
Salles, N.
这篇简短的综述的目的是总结近年来关于胃肠道随年龄变化的数据，重点是胃肠道动力障碍和粘膜变化。首先，这篇综述集中在随着年龄的增长，胃肠动力障碍，即使增加了几个胃肠运动障碍的患病率（即。例如，吞咽困难、消化不良、厌食和便秘）发生在老年人中，但衰老本身似乎对大多数胃肠道功能有轻微的直接影响。其次，本文重点介绍了衰老过程中的组织学变化。例如，胃肠道粘膜生长的调节、胃肠道癌变和胃粘膜变化，特别是胃酸分泌的变化、细菌过度生长及其对老年患者的后果。版权所有（C）2007 S. Karger AG，巴塞尔。
The goal of this short review is to summarize recent data on gastrointestinal changes with aging, focusing on gastrointestinal motility disorders, and mucosal variations. First of all, this review focused on gastrointestinal motility disorders with aging, even though an increased prevalence of several gastrointestinal motor disorders (i. e., dysphagia, dyspepsia, anorexia, and constipation) occurs in older people, aging per se appears to have a minor direct effect on most gastrointestinal functions. Secondly, this review focused on histological changes with aging, i. e., regulation of gastrointestinal mucosal growth, gastrointestinal carcinogenesis, and gastric mucosal changes, especially changes in gastric acid secretion, bacterial overgrowth and its consequences on elderly patients. Copyright (C) 2007 S. Karger AG, Basel.