THE USE OF HEALTH ECONOMICS IN THE EARLY EVALUATION OF REGENERATIVE MEDICINE APPLICATIONS
THE USE OF HEALTH ECONOMICS IN THE EARLY EVALUATION OF REGENERATIVE MEDICINE APPLICATIONS
复制标题
健康经济学在再生医学应用早期评估中的应用
DOI：
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发表时间：
2008
期刊：
影响因子：
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通讯作者：
R. Lilford
中科院分区：
文献类型：
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作者：
H. McAteer;R. Lilford
简介：在资源有限的医疗保健系统中，采购和报销决策越来越受到正式卫生经济分析的影响。因此，在开发周期尽早评估新技术的潜在成本效益是明智的。我们提出了新的使用卫生经济学在供应侧使用的方法，我们称之为净空方法1。我们会问这样一个问题：“如果这项技术像我们希望的那样有效，它是否具有成本效益？”我们已经将这种方法应用于泌尿生殖系统的临床应用，并正在研究腹壁和骨缺损的应用。方法：净空法可以估计一项技术可以推向市场的最大成本，并且仍然被认为是成本效益。为了应用这种方法，首先，该技术将解决的临床问题必须明确定义，重要的是要尽可能具体，清楚地了解目前治疗的优势和劣势至关重要，以及疾病的具体描述，包括患病率和发病率。这是通过全面和系统的文献综述以及与临床医生和组织工程师的咨询来实现的。这两个要素符合图1所述的更广泛的投资决策框架。
INTRODUCTION: In healthcare systems with finite resources purchasing and reimbursement decisions are increasingly influenced by formal health economic analysis. It is therefore sensible to assess potential costeffectiveness of a new technology as early as possible in the development cycle. We propose the novel use of health economics at the supply side using an approach we term the headroom method 1 . We ask the question ‘would it [the technology] be cost-effective if it works as well as we hope?’ We have applied this method to clinical applications in the urogenital system and are working on applications of abdominal wall and bone defects. METHODS: The headroom method can estimate the maximum cost for which a technology can be brought to market and still be considered cost-effective. In order to apply this method, firstly, the clinical problem which the technology will address must be clearly defined, it is important to be as specific as possible, a clear understanding of the strengths and weaknesses of current treatment is crucial as well as a specific description of disease including prevalence and incidence. This is achieved through a comprehensive and systematic review of literature and consultation with clinicians and tissue engineers. These two elements fit into a broader investment decision framework described in figure 1.