ANTIBACTERIAL MECHANISMS IN INTESTINE - ELIMINATION OF V CHOLERAE FROM GASTROINTESTINAL-TRACT OF ADULT MICE
ANTIBACTERIAL MECHANISMS IN INTESTINE - ELIMINATION OF V CHOLERAE FROM GASTROINTESTINAL-TRACT OF ADULT MICE
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DOI：
10.1038/icb.1975.14
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发表时间：
1975-01-01
期刊：
影响因子：
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通讯作者：
ROWLEY, D
中科院分区：
文献类型：
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作者：
KNOP, J;ROWLEY, D
32P标记的V的消除。对来自成年小鼠胃肠道的霍乱微生物进行了追踪。口服接种的霍乱弧菌活菌数量迅速减少。消除活细菌所涉及的参数是通过胃酸杀死、通过蠕动机械去除和在小肠中杀死。通过不同的处理来抑制这些参数中的一个或多个可延迟或阻止生物体的消除。在饥饿动物中获得的结果表明，小肠中的分泌过程有助于杀死生物体。
The elimination of32P‐labelledV. choleraeorganisms from the gastrointestinal tract of adult mice has been followed. Orally inoculated V.choleraeorganisms are rapidly reduced in viable numbers. The parameters involved in the elimination of the viable bacteria are killing by gastric acid, mechanical removal by peristalsis and killing in the small intestine. Inhibition of one or more of these parameters by different treatments delays or prevents the elimination of the organisms. Results obtained in starved animals suggest that secretory processes in the small intestine contribute to the killing of the organisms.